o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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OECD SIDS o-TOLUIDINE 6. REFERENCES ID: 95-53-4 DATE: 07.01.2005 282 (144) Lunkin VN (1967) Ref Zh Otd Vyp Farmakol Khimioter Sredstva Toksikol, No. 12.54.1096; cited in: American Conference of Governmental Industrial Hygienists, Inc.(ACGIH, 1986). Documentation of the Threshold Limit Values(TLV) and Biological Exposures, Indices(BEI), fifth edition, 1986: o-Toluidine, p. 586- 588 (145) Smyth HF JR, Carpenter CP, Weil CS, Pozzani UC, Striegel JA (1962) Range-Finding Toxicity Data List VI. Am Ind Hyg Ass J 23: 95-107 (146) Lindstrom HV, Bowie WC, Wallace WC, Nelson AA and Fitzhugh OG (1969) The toxicity and metabolism of Mesidine and Pseudocumidine in rats. J Pharmacol Exp Ther 167: 223- 234 (147) Senczuk W, Rucinska H (1984). Bromat. Chem. Toksykol. 17, 51; zitiert in: Toxikolog.arbeitsmed. Begruendung von MAK-Werten. VCH, Weinheim (1986). (148) Senczuk W and Rucinska H (1984). Toxicodynamic properties of toluidines. Part V: Methaemoglobin-genic action of toluidines. Bromat. Chem. Toksykol. 17, 241-243. (149) DuPont Chem (1981) Inhalation Median Lethal Concentration. December 22, 1981: NTIS/OTS 0570956 (150) Weisburger EK, Russfield AB, Homburger F, Bogner E, Van Dongen CG, Chu KC, (1978). Testing of twenty-one environmental aromatic aminies or derivatives for long-term toxicity or carcinogenicity. J Environm Pathol Toxicol 2: 325-356 (151) Bayer AG, Steinhoff D, Dycka (1981) Vergleichende Kanzerogenese Versuche mit 2,4- Toluylendiamin, 2,4/2,6-Toluylendianin 80/20, m-Phenylendiamin, o-Toluidin, p-Toluidin, 4,4'-Diaminodiphenylnethan, Benzidin, bei subkutaner Applikation an Ratten. Unpublished report No 10682, July 06, 1981 (152) DeSerres FJ, Ashby J (1981) Evaluation of short-term tests for cancerogens. Progress Mutation Research 1: 1-827 (153) Salamone MF (1981) Toxicity of 41 carcinogens and noncarcinogens analogs. Prog Mut Res 1: 682-685 (154) Bayer AG, Thyssen J (1979) Untersuchungen zur Haut- und Schleimhautverträglichkeit. Short report dated March 19, 1979 (155) Kleniewska D (1975) Studies on hypersensitivity to "para-group". Berufsdermatosen 23, 31- 36 (156) DuPont, Gerber KM (1994) Urinary bladder toxicity - 14-day feeding study with o-tuluidine in rats. Report DuPont HLR 699-93, OTS0557449 (157) National Cancer Institute (NCI) (1996) NTP Technical Report on Comparative Toxicity and Carcinogenicity Studies of o-Nitrotoluene and o-Toluidine Hydrochloride. Technical Report Series No. 44. NIH Publication No. 96-3936. (158) Short CR, King C, Sistrunk P, and Kriklyn MK (1983) Subacute Toxicity of Several Ring- Substituted Dialkyanilines in the Rat. Fund Appl Toxicol 3: 285-292 (159) National Cancer Institute (NCI) (1979) Bioassay of o-Toluidine Hydrochloride for possible carcinogenicity. Technical Report Series No. 153. NIH Publication No. 79-1709. (160) Ekman B, Stroembeck JP (1947) Demonstration of tumorigenic decomposition products of 2,3-azotoluene. Acta Physiol Scand 14: 43-50 UNEP PUBLICATIONS
OECD SIDS o-TOLUIDINE 6. REFERENCES ID: 95-53-4 DATE: 07.01.2005 (161) Ekman B, Stroembeck JP (1949) The effect of some splitproducts of 2,3'-azotoluene on the urinary bladder in the rat and their excretion of various diets. Acta Path Microbiol Scand 26: 447-471 (162) Morigami S, Nisimura I (1940) Experimental studies on aniline bladder tumors. Gann Jpn J Cancer Res 34, 146-147; cited Toxikolog.-arbeitsmed. Begruendung von MAK-Werten, VCH (1986) (163) Malysheva MV, Saitzeva EP, Ivanov YuV (1983) Effects after dermal application with otoluidine in rats. Gig Tr Prof Zabol 9: 47-49 (164) Microbiol Associates Inc., Valentine O (1996) Salmonella plate incorporation mutagenicity assay (Ames Test) with a confirmatory assay. Lab Study No TE344.501132, November 07, 1996 (at the request of Berufsgenossenschaft der Chemischen Industrie, Heidelberg) (165) Ashby J, Tennant RW (1988). Chemical Structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the US NCI/NTP. Mut. Res. 204, 17-115. (166) Zeiger E (1987). Carcinogenicity of Mutagens Predictive Capability of Salmonella Mutagenesis Assay for Rodent Carcinogenicity. Cancer Res. 47, 1287-1296. (167) Zeiger E, Haworth S (1985) Tests with a preincubation modification of Salmonella/microsome assay. Prog Mut Res 5: 187-199 (168) JETOC (Jap Chem Ind Ecolog Toxicol Inform Center) (1997) Mutagenicity Test Data of Existing Chemical Substances [Supplement]: 33-39, 244-246, February 1997 (169) Matsushima T, Maramatsu M, Haresaku M (1985) Mutation tests on Salmonella typhimurium by the preincubation methode. Prog Mut Res 5: 181-186 (170) Rexroat MA, Probst GS (1985) Mutation tests with Salmonella using the plate-incorporation assay. Prog Mut Res 5: 201-212 (171) Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K (1992) Salmonella Mutagenicity tests: V. Results from the testing of 311 chemicals. Environm Mol Mutagen 19, Suppl 21: 2- 141 (172) Fox M, Delow GF (1985) Tests for mutagenic activity at the HGPRT locus in Chinese hamster V79 cells in culture. Prog Mut Res 5: 517-523 (173) Garner RC (1985) Summary Report on the performance of gene mutation assays in mammalian cells in culture. Prog Mut Res 5: 85-94 (174) Kuroda Y (1984) Mutagenic activity of Ames test-negative carcinogens in cultured mammalian cells. Mut Res 30: 369-370 (175) Kuroda Y, Yokoiyama A, Kada T (1985) Assays for the induction of mutagens to 6thioguanine restance in Chinese hamster V79 cells culture. Prog Mut Res 5: 537-542 (176) Amacher DE, Turner GN (1985) Tests for gene mutational activity in the L5178Y/TK assay system. Prog. Mut Res 5: 487-496 (177) Myhr B, Bowers L, Caspari WJ (1985) Assays for the induction of gene mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells in culture. Prog Mut Res 5: 555- 568 (178) Dean BJ (1985) Summary Report on the performance of cytogenetic assays in cultured mammalian cells. Prog Mut Res 5: 69-83 UNEP PUBLICATIONS 283
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OECD SIDS o-TOLUIDINE FOREWORD INTR
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OECD SIDS o-TOLUIDINE 6 REFERENCES
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o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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