o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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OECD SIDS o-TOLUIDINE 4. ECOTOXICITY ID: 95-53-4 DATE: 07.01.2005 106 Test substance : other TS: o-Toluidine, purity is not specified Method : The test was carried out according to the static Golden Orfe test from Mann (1975): "Der Goldorfentest. Deutscher Vorschlag zur Prüfung der Wirkung von chemischen Stoffen auf Fische. Vom Wasser 44, 1-13", later on published in DEV L15: Fischtest (Bestimmung der Wirkung von Wasserinhaltsstoffen auf Fische). Preprint (1976) in: Vom Wasser 46, 291- 295. Method of the German Standards Institution, Berlin, Germany. Remark : 200 selected compounds were tested under comparable conditions in two different laboratories. Reliability : (2) valid with restrictions Study meets generally accepted scientific principles Flag : Critical study for SIDS endpoint 02.02.2004 (94) Type : semistatic Species : Poecilia reticulata (Fish, fresh water) Exposure period : 14 day(s) Unit : mg/l LC50 : = 81.3 Limit test : Analytical monitoring : no data Method : other: test procedure according to Koenemann H (1981). Toxicology 19, 209-221. Year : 1984 GLP : no Test substance : other TS: o-Toluidine, purity is not specified Method : Result was first publicated by Hermens (1984). Remark : Limited documentation Result : Experimental result is given as log LC50 (µmol/l): - Measured log LC50=2.88 (LC50=81.3 mg/l) Test condition : - 2 to 3 month-old guppies (Poecilia reticulata) were exposed to several concentrations of the solute in 1.5 l vessels. Eight guppies were tested at each concentration. - Each vessel was filled with 1 l of standard water (hardness 25 mg/l as CaCO3). - The test solution was renewed daily. - The guppies were fed 0.5 h before incubation with a commercial fish food. - Temperature = 22+/-1 °C - Oxygen content remained above 5 mg/l Test substance : In deviation to the test procedure according Koenemann the stock solution of o-toluidine was prepared in 2-propanol to avoide difficulties in GC analysis. Reliability : (2) valid with restrictions Study meets generally accepted scientific principles Flag : Critical study for SIDS endpoint 18.06.2004 (29) (95) (96) (97) (30) Type : static Species : Leuciscus idus (Fish, fresh water) Exposure period : 48 hour(s) Unit : mg/l LC0 : = 50 LC100 : = 100 Limit test : Analytical monitoring : no Method : other: Bestimmung der akuten Wirkung von Stoffen auf Fische. Arbeitskreis "Fischtest" im Hauptausschuss "Detergentien" (1973.10.15) Year : 1976 UNEP PUBLICATIONS
OECD SIDS o-TOLUIDINE 4. ECOTOXICITY ID: 95-53-4 DATE: 07.01.2005 GLP : no Test substance : other TS: o-Toluidine, purity is not specified Remark : This was a screening test: just 2 concentrations of o-toluidine were tested (50 and 100 mg/l) each time with 2 fishes. Reliability : (4) not assignable Documentation insufficient for assessment 11.02.2004 (98) Type : flow through Species : Cyprinus carpio (Fish, fresh water) Exposure period : 48 hour(s) Unit : mg/l LC50 : = 78.5 Limit test : Analytical monitoring : no data Method : other: no data Year : 1983 GLP : no data Test substance : other TS: o-Toluidine, purity is not specified Reliability : (4) not assignable Original reference in Japanese, only short abstract in English 11.02.2004 (90) (91) Type : flow through Species : Oryzias latipes (Fish, fresh water) Exposure period : 48 hour(s) Unit : mg/l LC50 : 100 Limit test : Analytical monitoring : no data Method : other: no data Year : 1983 GLP : no data Test substance : other TS: o-Toluidine, purity is not specified Reliability : (4) not assignable Original reference in Japanese, only short abstract in English 11.02.2004 (90) (91) Type : static Species : Oryzias latipes (Fish, fresh water) Exposure period : 48 hour(s) Unit : mg/l LC50 : 102.7 Limit test : Analytical monitoring : no data Method : other: no data Year : 1983 GLP : no data Test substance : other TS: o-Toluidine, purity is not specified Reliability : (4) not assignable Original reference in Japanese, only short abstract in English 11.02.2004 (90) (91) Type : flow through Species : Carassius auratus (Fish, fresh water) Exposure period : 48 hour(s) Unit : mg/l UNEP PUBLICATIONS 107
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OECD SIDS o-TOLUIDINE FOREWORD INTR
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OECD SIDS o-TOLUIDINE 11. Comments:
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OECD SIDS o-TOLUIDINE and transitio
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OECD SIDS o-TOLUIDINE countries), e
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OECD SIDS o-TOLUIDINE 1.3 Physico-C
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OECD SIDS o-TOLUIDINE Inhalation Th
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OECD SIDS o-TOLUIDINE 6 REFERENCES
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OECD SIDS o-TOLUIDINE Bringmann G,
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OECD SIDS o-TOLUIDINE Hecht SS, El-
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OECD SIDS o-TOLUIDINE phase extract
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OECD SIDS o-TOLUIDINE Stark M (1892
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OECD SIDS o-TOLUIDINE I U C L I D D
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o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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