o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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OECD SIDS o-TOLUIDINE 5. TOXICITY ID: 95-53-4 DATE: 07.01.2005 146 Number of animals : Vehicle : Doses : Route of admin. : i.p. Exposure time : Method : other:according Hagen EC (1959) Acute Toxicity. The Editorial Committee Association of Food and Drug Officials of the US Year : 1978 GLP : no Test substance : other TS: o-Toluidine hydrochloride, no data on purity Reliability : (4) not assignable Insufficient documentation 09.06.2004 (150) Type : LD50 Value : = 179 mg/kg bw Species : mouse Strain : CD-1 Sex : male Number of animals : Vehicle : Doses : Route of admin. : i.p. Exposure time : Method : other:according Hagen EC (1959) Acute Toxicity. The Editorial Committee Association of Food and Drug Officials of the US Year : 1978 GLP : no Test substance : other TS: o-Toluidine hydrochloride, no data on purity Reliability : (4) not assignable Insufficient documentation 02.06.2004 (150) Type : LD50 Value : = 113 mg/kg bw Species : mouse Strain : CD-1 Sex : female Number of animals : Vehicle : Doses : Route of admin. : i.p. Exposure time : Method : other:according Hagen EC (1959) Acute Toxicity. The Editorial Committee Association of Food and Drug Officials of the US Year : 1978 GLP : no Test substance : other TS: o-Toluidine hydrochloride, no data on purity Reliability : (4) not assignable Insufficient documentation 02.06.2004 (150) Type : LD50 Value : = 1115 mg/kg bw Species : rat Strain : Sprague-Dawley Sex : female Number of animals : UNEP PUBLICATIONS
OECD SIDS o-TOLUIDINE 5. TOXICITY ID: 95-53-4 DATE: 07.01.2005 Vehicle : peanut oil Doses : Route of admin. : s.c. Exposure time : Method : other: dose finding for a cancerogenicity study see RE Year : 1981 GLP : no Test substance : as prescribed by 1.1 - 1.4 Result : LD50 = 1115 mg/kg body weight 95 % confidence limit: 984 - 1295 mg/kg bw Test condition : TEST ORGANISMS: - Animals: female Sprague Dawley rats - Age: 6 weeks ADMINISTRATION: - Route: subcutan - Vehicle: peanut oil - Doses per time period: single dose - Post dose observation period: 3 weeks Reliability : (2) valid with restrictions Insufficient documentation, investigated for dose finding only 12.06.2003 (151) Type : LD50 Value : = 338 ml/kg bw Species : mouse Strain : B6C3F1 Sex : male Number of animals : 5 Vehicle : other: DMSO Doses : Route of admin. : i.p. Exposure time : Method : other : LD50 calculated from the tables Thompson and Weil, 1952 Year : 1981 GLP : no data Test substance : other TS: see freetext TC Test condition : This study is part of a International Collaborative Program, published as: Evaluation of Short-Term Tests for Cancerogens Progress in Mutation Research Vol 1. Edited by Frederick J. Serres and John Ashby, 1981 CHEMICALS: 42 coded chemicals were investigated in short-term tests for cancerogenicity in different laboratories It should be suggested that only 100%-pure chemicals should be used when evaluating a test system. In the present work the compound with code no 41 is declared as otoluidine hydrochloride, whereas in an the overall summary of this program code no. 41 is declared as o-toluidine. Reliability : (4) not assignable Unsuitable test system 02.06.2004 (152) (153) 5.2.1 SKIN IRRITATION Species : rabbit Concentration : undiluted UNEP PUBLICATIONS 147
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OECD SIDS o-TOLUIDINE FOREWORD INTR
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OECD SIDS o-TOLUIDINE 11. Comments:
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OECD SIDS o-TOLUIDINE and transitio
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OECD SIDS o-TOLUIDINE 6 REFERENCES
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OECD SIDS o-TOLUIDINE Bringmann G,
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OECD SIDS o-TOLUIDINE Hecht SS, El-
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OECD SIDS o-TOLUIDINE phase extract
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OECD SIDS o-TOLUIDINE Stark M (1892
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OECD SIDS o-TOLUIDINE I U C L I D D
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o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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