o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
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OECD SIDS o-<strong>TOLUIDINE</strong><br />
4. ECOTOXICITY ID: <strong>95</strong>-<strong>53</strong>-4<br />
DATE: 07.01.2005<br />
112<br />
Study meets generally accepted scientific principles<br />
13.01.2004 (101)<br />
Type : static<br />
Species : Daphnia magna (Crustacea)<br />
Exposure period : 24 hour(s)<br />
Unit : mg/l<br />
EC0 : 1.6 - 5<br />
EC50 : 9 - 50<br />
EC100 : 100<br />
Analytical monitoring : no<br />
Method : other: Immobilization test according to Bringmann G and Kuehn R (1977)<br />
Z. Wasser Abwasser Forsch. 10, 161-166<br />
Year : 1977<br />
GLP : no<br />
Test substance : other TS: o-Toluidine, purity is not specified<br />
Remark : Effect endpoint: Immobilization<br />
Result : Effect values refer to nominal test substance concentrations.<br />
Reference substance: potassium dichromate, EC50 (average value) = 1.3<br />
mg/l (required range: 0.9 - 1.9 mg/l)<br />
Test condition : The test was performed under the following conditions:<br />
- Test organism: Daphnia magna Straus, standardized test strain IRCHA<br />
(max. age 24 h old), Temperature = 20 °C (incubator)<br />
- Test vessels were loosely capped with filter paper<br />
- Testing was performed in a chemically and physically defined<br />
standardized culture medium according to DIN-Standard 38412 part 11<br />
(artificial fresh water)<br />
- Dilution water: Source = synthetic fresh water, 2.5 mmol/l Ca+Mg, Na/K<br />
ratio=10:1<br />
- Initial pH=8.0+/-0.2 (not adjusted during exposure)<br />
- Duplicate parallel dilution series with 10 daphnids / vessel (10 organisms /<br />
20 ml)<br />
- Stock cultures were fed with standardized dry algae<br />
- Oxygen content and pH were measured at the beginning and at the end<br />
of the test.<br />
Reliability : (2) valid with restrictions<br />
Study meets generally accepted scientific principles<br />
19.12.2003 (102)<br />
Type : static<br />
Species : Elasmopus pectenicrus (Crustacea)<br />
Exposure period : 96 hour(s)<br />
Unit : mg/l<br />
LC50 : > 40<br />
Analytical monitoring : no<br />
Method : other: no data<br />
Year : 1978<br />
GLP : no<br />
Test substance : other TS: o-Toluidine, purity is not specified<br />
Method : To estimate the 24, 48 and 96 h LC50 values for each solution, the method<br />
of Litchfield and Wilcoxon (1949) was employed.<br />
Remark : - The toxicity of o-toluidine was also tested in the presence of naphthalene,<br />
o-cresole, and/or 1,2,4-trimethylbenzene.<br />
- It is not usual that the organisms are fed during the test. This may affect<br />
the test result.<br />
Result : Other results:<br />
24 h-LC50 > 40 mg/l<br />
48 h-LC50 > 40 mg/l<br />
<strong>UNEP</strong> PUBLICATIONS
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