o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
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OECD SIDS o-<strong>TOLUIDINE</strong><br />
4. ECOTOXICITY ID: <strong>95</strong>-<strong>53</strong>-4<br />
DATE: 07.01.2005<br />
106<br />
Test substance : other TS: o-Toluidine, purity is not specified<br />
Method : The test was carried out according to the static Golden Orfe test from Mann<br />
(1975): "Der Goldorfentest. Deutscher Vorschlag zur Prüfung der Wirkung<br />
von chemischen Stoffen auf Fische. Vom Wasser 44, 1-13", later on<br />
published in DEV L15: Fischtest (Bestimmung der Wirkung von<br />
Wasserinhaltsstoffen auf Fische). Preprint (1976) in: Vom Wasser 46, 291-<br />
2<strong>95</strong>.<br />
Method of the German Standards Institution, Berlin, Germany.<br />
Remark : 200 selected compounds were tested under comparable conditions in two<br />
different laboratories.<br />
Reliability : (2) valid with restrictions<br />
Study meets generally accepted scientific principles<br />
Flag : Critical study for SIDS endpoint<br />
02.02.2004 (94)<br />
Type : semistatic<br />
Species : Poecilia reticulata (Fish, fresh water)<br />
Exposure period : 14 day(s)<br />
Unit : mg/l<br />
LC50 : = 81.3<br />
Limit test :<br />
Analytical monitoring : no data<br />
Method : other: test procedure according to Koenemann H (1981). Toxicology 19,<br />
209-221.<br />
Year : 1984<br />
GLP : no<br />
Test substance : other TS: o-Toluidine, purity is not specified<br />
Method : Result was first publicated by Hermens (1984).<br />
Remark : Limited documentation<br />
Result : Experimental result is given as log LC50 (µmol/l):<br />
- Measured log LC50=2.88 (LC50=81.3 mg/l)<br />
Test condition : - 2 to 3 month-old guppies (Poecilia reticulata) were exposed to several<br />
concentrations of the solute in 1.5 l vessels. Eight guppies were tested at<br />
each concentration.<br />
- Each vessel was filled with 1 l of standard water (hardness 25 mg/l as<br />
CaCO3).<br />
- The test solution was renewed daily.<br />
- The guppies were fed 0.5 h before incubation with a commercial fish food.<br />
- Temperature = 22+/-1 °C<br />
- Oxygen content remained above 5 mg/l<br />
Test substance : In deviation to the test procedure according Koenemann the stock solution<br />
of o-toluidine was prepared in 2-propanol to avoide difficulties in GC<br />
analysis.<br />
Reliability : (2) valid with restrictions<br />
Study meets generally accepted scientific principles<br />
Flag : Critical study for SIDS endpoint<br />
18.06.2004 (29) (<strong>95</strong>) (96) (97) (30)<br />
Type : static<br />
Species : Leuciscus idus (Fish, fresh water)<br />
Exposure period : 48 hour(s)<br />
Unit : mg/l<br />
LC0 : = 50<br />
LC100 : = 100<br />
Limit test :<br />
Analytical monitoring : no<br />
Method : other: Bestimmung der akuten Wirkung von Stoffen auf Fische. Arbeitskreis<br />
"Fischtest" im Hauptausschuss "Detergentien" (1973.10.15)<br />
Year : 1976<br />
<strong>UNEP</strong> PUBLICATIONS
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