o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals
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OECD SIDS o-<strong>TOLUIDINE</strong><br />
3. ENVIRONMENTAL FATE AND PATHWAYS ID: <strong>95</strong>-<strong>53</strong>-4<br />
DATE: 07.01.2005<br />
Contact time :<br />
Degradation : 88 - 90 (±) % after 28 day(s)<br />
Result : readily biodegradable<br />
Deg. product :<br />
Method : OECD Guide-line 301 A (old version) "Ready Biodegradabiltiy: Modified<br />
AFNOR Test"<br />
Year : 1983<br />
GLP : no<br />
Test substance : other TS: o-Toluidine, purity is not specified<br />
Method : - Tests were carried out using an inoculum prepared from the same source<br />
which was recommended to be the final effluent from a sewage works<br />
treating predominantly domestic sewage.<br />
The concentration stage required was achieved by either membrane<br />
filtration or centrifugation (inoculum density was between 2E+07 and<br />
5E+05 bacteria/ml), although one of the six laboratories used activated<br />
sludge (30 mg/l)<br />
- Reference compound control: aniline (validity criterion: 70 % aniline<br />
degradation by day 14); analysis both by DOC and substance specific<br />
analysis (GC)<br />
Remark : Six laboratories took part following the same protocol which specified the<br />
details of the test procedure.<br />
Biodegradation was referred to DOC-elimination.<br />
No sterile or toxicity control were performed.<br />
Result : The days for analysis were 0, 3, 7, 14, 21 and 28 and analysis by both<br />
DOC and by specific analysis (gas chromatography recommended) was<br />
specified.<br />
The pass level of 70 % was reached after 7 days (10 days window<br />
criterion) in all experiments.<br />
One of the labs presented 2 series of results, as in the first experiment an<br />
extreme low degradation was obtained which was not in accordance with<br />
all other results. The results of the first series were therefore not<br />
considered.<br />
Reliability : (2) valid with restrictions<br />
Test procedure in accordance with standard guideline with acceptable<br />
modifications<br />
Flag : Critical study for SIDS endpoint<br />
15.06.2004 (71)<br />
Type : aerobic<br />
Inoculum : activated sludge<br />
Concentration : 2.4 mg/l related to Test substance<br />
related to<br />
Contact time :<br />
Degradation : 83 (±) % after 20 day(s)<br />
Result : readily biodegradable<br />
Kinetic of testsubst. : 5 day(s) 0 %<br />
10 day(s) 78 %<br />
20 day(s) 83 %<br />
%<br />
%<br />
Deg. product : not measured<br />
Method : other: Closed Bottle Test, comparable to OECD TG 301 D<br />
Year : 1976<br />
GLP : no<br />
Test substance : other TS: o-Toluidine, purity is not specified<br />
Reliability : (4) not assignable<br />
<strong>UNEP</strong> PUBLICATIONS 91
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