o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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OECD SIDS o-TOLUIDINE 4. ECOTOXICITY ID: 95-53-4 DATE: 07.01.2005 126 Year : 1984 GLP : no data Test substance : other TS: o-Toluidine, purity > 99.5 % Method : Dutch Standardization Organization, Rijswijk, The Netherlands (1980) Remark : The author confirmed in a personal communication, the 22nd of June 2004 to Bayer Industry Services OHG that the range of concentrations tested was always the same for each test substance: 0.01, 0.032, 0.1, 0.32, 01.0, 3.2, 10.0 mg/l. In the summary table of the publication only the LRCT (LOEC) of the otoludine was reported. According to the statement made by the author, the NOEC value corresponds to 0.032 mg/l. The daphnids were fed with 3.0E+08 cells/l Chorella pyrenoidosa. Result : Three chronic effects are presented. 1. Population growth: LRCT (Rm)= Lowest rejected concentration tested which significantly lowered the population growth constant (Rm) after 21 days of exposure: LRCT (Rm)=0.1 mg/l 2. Body length: LRCT (L)=Lowest rejected concentration tested which significantly lowered the mean length (L) of animals after 21 days of exposure: LRCT (L)=1.0 mg/l 3. Immobilization: IC50 = 21 days immobilization concentration 21 d-IC50= 2.2 mg/l Test condition : - The population growth constant (Rm) of Daphnia magna was determined under semistatic conditions over a 21 days period, using 10 daphnids per concentration and one animal per jar containing 10 ml medium. - The test was carried out in a room at a temperature of 20 °C illuminated 12h/day. A synthetic medium was used with a hardness of 200 mg/l CaCO3 and a pH of 8.4. Reliability : (2) valid with restrictions Test procedure in accordance with national standard methods Flag : Critical study for SIDS endpoint 10.11.2004 (30) 4.6.1 TOXICITY TO SEDIMENT DWELLING ORGANISMS 4.6.2 TOXICITY TO TERRESTRIAL PLANTS 4.6.3 TOXICITY TO SOIL DWELLING ORGANISMS 4.6.4 TOX. TO OTHER NON MAMM. TERR. SPECIES 4.7 BIOLOGICAL EFFECTS MONITORING 4.8 BIOTRANSFORMATION AND KINETICS UNEP PUBLICATIONS
OECD SIDS o-TOLUIDINE 4. ECOTOXICITY ID: 95-53-4 DATE: 07.01.2005 4.9 ADDITIONAL REMARKS UNEP PUBLICATIONS 127
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o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

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