o-TOLUIDINE CAS N°: 95-53-4 - UNEP Chemicals

OECD SIDS o-TOLUIDINE
4. ECOTOXICITY ID: 95-53-4
DATE: 07.01.2005
126
Year : 1984
GLP : no data
Test substance : other TS: o-Toluidine, purity > 99.5 %
Method : Dutch Standardization Organization, Rijswijk, The Netherlands (1980)
Remark : The author confirmed in a personal communication, the 22nd of June 2004
to Bayer Industry Services OHG that the range of concentrations tested
was always the same for each test substance: 0.01, 0.032, 0.1, 0.32, 01.0,
3.2, 10.0 mg/l.
In the summary table of the publication only the LRCT (LOEC) of the otoludine
was reported. According to the statement made by the author, the
NOEC value corresponds to 0.032 mg/l.
The daphnids were fed with 3.0E+08 cells/l Chorella pyrenoidosa.
Result : Three chronic effects are presented.
1. Population growth:
LRCT (Rm)= Lowest rejected concentration tested which significantly
lowered the population growth constant (Rm) after 21 days of exposure:
LRCT (Rm)=0.1 mg/l
2. Body length:
LRCT (L)=Lowest rejected concentration tested which significantly lowered
the mean length (L) of animals after 21 days of exposure:
LRCT (L)=1.0 mg/l
3. Immobilization:
IC50 = 21 days immobilization concentration
21 d-IC50= 2.2 mg/l
Test condition : - The population growth constant (Rm) of Daphnia magna was determined
under semistatic conditions over a 21 days period, using 10 daphnids per
concentration and one animal per jar containing 10 ml medium.
- The test was carried out in a room at a temperature of 20 °C illuminated
12h/day. A synthetic medium was used with a hardness of 200 mg/l
CaCO3 and a pH of 8.4.
Reliability : (2) valid with restrictions
Test procedure in accordance with national standard methods
Flag : Critical study for SIDS endpoint
10.11.2004 (30)
4.6.1 TOXICITY TO SEDIMENT DWELLING ORGANISMS
4.6.2 TOXICITY TO TERRESTRIAL PLANTS
4.6.3 TOXICITY TO SOIL DWELLING ORGANISMS
4.6.4 TOX. TO OTHER NON MAMM. TERR. SPECIES
4.7 BIOLOGICAL EFFECTS MONITORING
4.8 BIOTRANSFORMATION AND KINETICS
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