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m-Cresol - ipcs inchem

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OECD SIDS<br />

m-CRESOL<br />

4. ECOTOXICITY ID: 108-39-4<br />

DATE: 24.05.2004<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : described in: Denson & Bold, The University of Texas<br />

Publication No. 6022, 72 (1960)<br />

Remark : MTL = median tolerance limit<br />

Result : sublethal concentration 100 mg/l<br />

lethal concentration 500 mg/l<br />

Reliability : (4) not assignable<br />

Insufficient documentation<br />

12.05.2004 (78)<br />

4.4 TOXICITY TO MICROORGANISMS E.G. BACTERIA<br />

Type : aquatic<br />

Species : activated sludge, domestic<br />

Exposure period : 3 hour(s)<br />

Unit : mg/l<br />

EC50 : 461.4<br />

Analytical monitoring : no<br />

Method : OECD Guide-line 209 "Activated Sludge, Respiration Inhibition Test"<br />

Year : 1985<br />

GLP : no<br />

Test substance : other TS: m-cresol, reagent grade<br />

Remark : synthetic sewage stock solution slightly different from OECD<br />

guideline; reference substance 1,5-dichlorophenol<br />

Test condition : 21 degrees C; continuous aeration with 0.5-10 l/min<br />

Reliability : (1) valid without restriction<br />

Guideline study<br />

Flag : Critical study for SIDS endpoint<br />

07.05.2004 (79)<br />

Type : aquatic<br />

Species : activated sludge of a predominantly domestic sewage<br />

Exposure period :<br />

Unit : mg/l<br />

EC75 : 11.4<br />

Analytical monitoring : no<br />

Method : other: inhibition of nitrification process<br />

Year : 1966<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : Quantitative determination of the nitrification rate (1st<br />

step, NH4 to NO2),<br />

colorimetric measurement of the NO2/NO3 concentration;<br />

static test system<br />

Pre-cleaned activated sludge in particle-free communal waste<br />

water (BOD5: 250 mg/l; NH4-N/l: 50-80 mg)<br />

Remark : effect: inhibition of ammonia oxidation<br />

Test condition : Exposure period: 2-4 h; 25 degree C; pH 7.6-7.8<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

sufficient documentation<br />

Flag : Critical study for SIDS endpoint<br />

07.05.2004 (80)<br />

104<br />

UNEP PUBLICATIONS

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