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m-Cresol - ipcs inchem

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OECD SIDS<br />

p-CRESOL<br />

4. ECOTOXICITY ID: 106-44-5<br />

DATE: 24.05.2004<br />

Endpoint : other: Photosynthesis and Respiration<br />

Exposure period :<br />

Unit :<br />

Limit test :<br />

Analytical monitoring : no<br />

Method :<br />

Year : 1983<br />

GLP : no<br />

Test substance : other TS: p-cresol, purity at least 99 %<br />

Method : Algae exposed in a open channel experimental stream set.<br />

Result : The net oxygen production decreased from 0.084 (control) to<br />

0.022 mg O2/mg DW with 8 mg/l TS. Respiration in the dark<br />

increased from -0.064 (control) to -0.182 O2/mg DW.<br />

Reliability : (3) invalid<br />

Unsuitable test system<br />

07.05.2004 (104)<br />

4.4 TOXICITY TO MICROORGANISMS E.G. BACTERIA<br />

238<br />

Type : aquatic<br />

Species : activated sludge of a predominantly domestic sewage<br />

Exposure period : 2 hour(s)<br />

Unit : mg/l<br />

IC50 : = 439.5 calculated<br />

Analytical monitoring : no<br />

Method : other: similar to OECD Guideline 209<br />

Year : 1999<br />

GLP : no<br />

Test substance : other TS: p-cresol, analytical grade<br />

Method : O2 measured with an optical scanning respirometer; endpoint:<br />

inhibition of respiration rate<br />

Test condition : pH 7.0; temp. 20 degrees C<br />

Reliability : (2) valid with restrictions<br />

Study in accordance with generally accepted scientific<br />

standards and described in sufficient detail<br />

Flag : Critical study for SIDS endpoint<br />

07.05.2004 (105)<br />

Type : aquatic<br />

Species : activated sludge of a predominantly domestic sewage<br />

Exposure period :<br />

Unit : mg/l<br />

EC75 : = 16.5<br />

Analytical monitoring : no<br />

Method : other: inhibition of nitrification process<br />

Year : 1966<br />

GLP : no<br />

Test substance : other TS: p-cresol, no purity reported<br />

Method : Quantitative determination of the nitrification rate (1st<br />

step, NH4 to NO2)<br />

colorimetric measurement of the NO2/NO3 concentration;<br />

static test system<br />

pre-cleaned activated sludge in particle-free communal waste<br />

water (BOD5: 250 mg/l; NH4-N/l: 50-80 mg)<br />

Remark : effect: inhibition of ammonia oxidation<br />

Test condition : Exposure period: 2-4h; 25 degree C; pH 7.6-7.8<br />

Reliability : (2) valid with restrictions<br />

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