m-Cresol - ipcs inchem

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OECD SIDS p-CRESOL 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 106-44-5 DATE: 24.05.2004 Deg. product : yes Method : Year : 1990 GLP : no Test substance : other TS: p-cresol, no purity reported (obtained from Aldrich) Deg. products : 123-08-0 204-599-1 4-hydroxybenzaldehyde 65-85-0 200-618-2 benzoic acid 74-82-8 200-812-7 methane 99-96-7 202-804-9 4-hydroxybenzoic acid Method : Sediment samples from a freshwater pond; degradation tested under three reducing conditions: denitrifying, sulfidogenic, and methanogenic Result : TS was completely utilized within 6 to 10 days in acclimated sediment. p- <strong>Cresol</strong> degradation proceeded through p-hydroxybenzaldehyde and p- hydroxybenzoate under methanogenic and denitrifying conditions. Under methanogenic conditions, also dehydroxylation to benzoic acid took place Test condition : - 30 degrees C in the dark - head space gas in the methanogenogenic and sulfidogenic cultures: CO2/N2 (30 %/70 %) - head space gas in the denitrifying cultures: argon - cultures were acclimated to p-cresol by 2 - 3 feedings of p-cresol Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 07.05.2004 (70) Type : aerobic Inoculum : activated sludge, domestic, non-adapted Concentration : 30 mg/l related to Test substance 100 mg/l related to Test substance Contact time : 1.5 day(s) Degradation : (±) % after Result : Kinetic of testsubst. : 2 day(s) = 100 % % % % % Deg. product : yes Method : other: Sapromat test Year : 1972 GLP : no Test substance : other TS: p-cresol, no purity reported Reliability : (3) invalid Insufficient documentation 07.05.2004 (71) Type : aerobic Inoculum : other: soil microorganisms Contact time : Degradation : 100 (±) % after 1 day(s) Result : Deg. product : no Method : Year : 1966 GLP : no Test substance : other TS: p-cresol, no purity reported Method : Inoculation in a 1% suspension of silt loam 218 UNEP PUBLICATIONS
OECD SIDS p-CRESOL 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 106-44-5 DATE: 24.05.2004 TS analyzed photometrically Reliability : (3) invalid Unsuitable test system 24.05.2004 (72) Type : anaerobic Inoculum : other: microcosm containing aquifer and ground water Concentration : 8 mg/l related to Test substance related to Deg. product : yes Method : Year : 1989 GLP : no data Test substance : other TS: p-cresol, no purity reported Deg. products : 74-82-8 200-812-7 methane Method : methanogenic conditions in a microcosm, presumably 10 °C Result : lag time 100 days, disappearance after approx. 180 d (values taken from a graphics) Reliability : (3) invalid Insufficient documentation 24.05.2004 (73) Type : aerobic Inoculum : other: river water and sea water Concentration : 10 mg/l related to Test substance 100 mg/l related to Test substance Contact time : 3 day(s) Degradation : 5 - 100 (±) % after 3 day(s) Result : Deg. product : Method : other: cultivation method Year : 1987 GLP : Test substance : other TS: p-cresol, no purity reported in abstract Result : The authors assume the compound to be easily biodegradable: with 10 ppm: Biodegradation in river water = 100% (3 repl) with 10 ppm: Biodegradation in sea water = 100% (3 repl) with 100 ppm: Biodegradation in river water = 100% (1 repl) with 100 ppm: Biodegradation in sea water = 5% (1 repl) Reliability : (4) not assignable Publication in Japanese, short abstract in English 24.05.2004 (74) 3.6 BOD5, COD OR BOD5/COD RATIO 3.7 BIOACCUMULATION Species : Oncorhynchus mykiss (Fish, fresh water) Exposure period : 6 hour(s) at 11 °C Concentration : 3.82 µg/l Elimination : no Method : Year : 1985 GLP : no Test substance : other TS: p-cresol, purity > 98 % (supplied by Pathfinder Laboratories, St. Louis) UNEP PUBLICATIONS 219
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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OECD SIDS m-CRESOL 6. REFERENCES ID
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OECD SIDS m-CRESOL 6. REFERENCES ID
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OECD SIDS m- / p-CRESOL MIXTURE I U
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OECD SIDS m- / p-CRESOL MIXTURE 1.
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