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m-Cresol - ipcs inchem

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OECD SIDS<br />

m- / p-CRESOL MIXTURE<br />

4. ECOTOXICITY ID: 15831-10-4<br />

DATE: 24.05.2004<br />

TEST SYSTEM<br />

- Concentrations: 1:2 dilution series<br />

- Number of replicates: 2<br />

- fish per replicate: 10<br />

- Test temperature: 14 degrees C<br />

- Dissolved oxygen: 6.5 mg/l (84.5% of saturation)<br />

- pH: 8.1<br />

- Photoperiod: 16 h light, 8 h dark<br />

Reliability : (1) valid without restriction<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

detailed documentation of test procedure and test conditions<br />

Flag : Critical study for SIDS endpoint<br />

11.02.2003 (42)<br />

Type : static<br />

Species : Salmo trutta (Fish, fresh water, marine)<br />

Exposure period : 96 hour(s)<br />

Unit : mg/l<br />

LC50 : = 8.4<br />

Limit test :<br />

Analytical monitoring : no<br />

Method :<br />

Year : 1969<br />

GLP : no<br />

Test substance : other TS: m-cresol, reported to be "purified grade"<br />

Method : 10 acclimated fish exposed per concentration, 20 served as<br />

controls.<br />

Result : LC50 (6 h) = 11.0 mg/l<br />

LC50 (24 h) = 8.6 mg/l<br />

LC50 (48 h) = 8.4 mg/l<br />

Test condition : 12 degree C, reconstituted water<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

sufficient documentation<br />

Flag : Critical study for SIDS endpoint<br />

12.05.2004 (43)<br />

Type : static<br />

Species : Salvelinus fontinalis (Fish, estuary, fresh water)<br />

Exposure period : 96 hour(s)<br />

Unit : mg/l<br />

LC50 : = 7.6<br />

Limit test :<br />

Analytical monitoring : no<br />

Method :<br />

Year : 1969<br />

GLP : no<br />

Test substance : other TS: m-cresol, reported to be "purified grade"<br />

Method : 10 acclimated fish exposed per concentration, 20 served as<br />

controls.<br />

Result : LC50 (6 h) = 11.4 mg/l<br />

LC50 (24 h) = 8.2 mg/l<br />

LC50 (48 h) = 7.6 mg/l<br />

at concentrations of 6 to 20 mg/l, the approximate<br />

incidences of surfacing were 20 %<br />

Test condition : 12 degree C, reconstituted water<br />

Reliability : (2) valid with restrictions<br />

UNEP PUBLICATIONS 327

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