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m-Cresol - ipcs inchem

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OECD SIDS<br />

p-CRESOL<br />

4. ECOTOXICITY ID: 106-44-5<br />

DATE: 24.05.2004<br />

Unit : mg/l<br />

EC50 : = 160<br />

Analytical monitoring : No<br />

Method :<br />

Year : 1985<br />

GLP : no data<br />

Test substance : other TS: p-cresol; purity analytical grade<br />

Method : The test was carried out under sterile conditions. T.<br />

pyriformis was pre-cultured at 30 degree C for 24 hours.<br />

The stock solution of chemical was added to the sterile<br />

medium to provide a constant ratio of 1.8 in 10 ml of 2%<br />

protose peptone. The solutions were then inoculated with<br />

0.2 ml T. pyriformis and cultivated for 24 hours at 30<br />

degree C without agitation. The number of cells were<br />

counted manually under a microscope (repeated 3 times) and<br />

with a Coulter Counter, Model Zb (repeated twice). Mean<br />

values were recorded with each method. Correlation<br />

coefficient between manual and Couter Counter was 0.998.<br />

Reliability : (2) valid with restrictions<br />

No standard test procedure, but in accordance with generally<br />

accepted scientific standards and described in sufficient<br />

detail<br />

24.10.2001 (110)<br />

Type : Aquatic<br />

Species : other bacteria: Aerobic heterotrophs<br />

Exposure period : 49 hour(s)<br />

Unit : mg/l<br />

IC50 : = 260<br />

Analytical monitoring : No<br />

Method :<br />

Year : 1991<br />

GLP : No<br />

Test substance : other TS: p-cresol, no purity reported<br />

Method : culture obtained from mixed liquor of a treatment plant<br />

Remark : Effect: inhibition of respiration; prolonged incubation<br />

compared with ISO 8192<br />

Test condition : 25 and 35 degrees C<br />

Reliability : (2) valid with restrictions<br />

Study in accordance with generally accepted scientific<br />

standards and described in sufficient detail<br />

07.05.2004 (107)<br />

Type : Aquatic<br />

Species : other bacteria: Methanogenic bacteria<br />

Exposure period : 96 hour(s)<br />

Unit : mg/l<br />

IC50 : = 91<br />

Analytical monitoring : No<br />

Method : other: Owen, W.F.: Bioassay for Monitoring Biochemical Methane Potential<br />

and Anaerobic Toxicity. Water Res. 13, 485 (1979)<br />

Year : 1991<br />

GLP : No<br />

Test substance : other TS: p-cresol, no purity reported<br />

Remark : Effect: Inhibition of gas production (CH4 + CO2)<br />

Test condition : 35 degrees C<br />

Reliability : (2) valid with restrictions<br />

Study in accordance with generally accepted scientific<br />

240<br />

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