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m-Cresol - ipcs inchem

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OECD SIDS<br />

p-CRESOL<br />

4. ECOTOXICITY ID: 106-44-5<br />

DATE: 24.05.2004<br />

Test condition : TEST ORGANISMS<br />

- Strain: IRCHA strain<br />

- Age: 24 h<br />

DILUTION WATER<br />

- Source: synthetic fresh water<br />

- Hardness: 2.5 mmol/l Ca + Mg<br />

- Na/K ratio: 10:1<br />

- pH: 8.0 +- 0.2<br />

TEST SYSTEM<br />

- Number of replicates: 4<br />

- individuals per replicate: 20<br />

- Test temperature: 25 +- 1 degrees C<br />

Reliability : (2) valid with restrictions<br />

Test procedure according to national guideline<br />

Flag : Critical study for SIDS endpoint<br />

07.05.2004 (92) (93)<br />

Type : static<br />

Species : Daphnia magna (Crustacea)<br />

Exposure period : 48 hour(s)<br />

Unit : mg/l<br />

EC0 : = 3.1<br />

EC50 : = 7.7<br />

EC100 : = 12.5<br />

Analytical monitoring : no<br />

Method : other: DIN 38412, part 11<br />

Year : 1989<br />

GLP : no<br />

Test substance : other TS: p-cresol, no purity reported<br />

Result : EC0 (24 h) = 6.3 mg/l<br />

EC50 (24 h) = 14 mg/l<br />

EC100 (24 h) = 50 mg/l<br />

all values are nominal<br />

Reliability : (2) valid with restrictions<br />

Test procedure according to national guideline<br />

07.05.2004 (94)<br />

Type : static<br />

Species : Daphnia magna (Crustacea)<br />

Exposure period : 24 hour(s)<br />

Unit : mg/l<br />

EC50 : = 12.4<br />

Analytical monitoring : no<br />

Method : other: AFNOR (1974)<br />

Year : 1987<br />

GLP : no data<br />

Test substance : other TS: p-cresol, purity > 95 %<br />

Remark : Effect: immobilisation<br />

Result : Result is reported as 24-h IC50 "0.115 mmol/l" (which equals 12.4 mg/l)<br />

Test condition : Reconstituted hard water, 200 mg/l CaCO3, pH 7.8-8.2<br />

dissolved oxigen >25% of saturation<br />

Reliability : (2) valid with restrictions<br />

Study in accordance with generally accepted scientific<br />

standards and described in sufficient detail<br />

07.05.2004 (95) (96)<br />

Type :<br />

Species : Daphnia magna (Crustacea)<br />

Exposure period : 48 hour(s)<br />

UNEP PUBLICATIONS 233

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