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OECD SIDS<br />

p-CRESOL<br />

6. REFERENCES ID: 106-44-5<br />

DATE: 24.05.2004<br />

(155) Hazleton Laboratories America Inc. (1988) HLA Study No. 10002-0-431 Mutagenicity test<br />

on meta-cresol in a mouse lymphoma mutation assay, Kensington, USA (at the request of<br />

CMA), EPA-OTS0517693<br />

(156) Daugherty JP and Franks H (1986) Effect of monocyclic derivatives on DNA repair in<br />

human lymphocytes. Res Commun Chem Path Pharmac 54: 133-136<br />

(157) Jansson T, Curvall M, Hedin A, Enzell CR (1986) In vitro studies of biological effects of<br />

cigarette smoke condensate II. Induction of sister-chromatid exchanges in human<br />

lymphocytes by weakly acidic, semivolatile constituents. Mutation Res 169: 129-139<br />

(158) Pool BL and Lin PZ (1982) Mutagenicity testing in the Salmonella Typhimurium assay of<br />

phenolic compounds and phenolic fractions obtained from smokehouse smoke<br />

condensates. Food Chem Toxicol 20: 383-391<br />

(159) Cheng M and Kligerman AD (1984) Evaluation of the genotoxicity of cresols using sisterchromatid<br />

exchange (SCE). Mutation Res 137: 51-55<br />

(160) Florin I, Rutberg L, Curvall M, Enzell CR (1980) Screening of tobacco smoke constituents<br />

for mutagenicity using the Ames'test. Toxicol 18: 219-232<br />

(161) Crowley JP and Margard W (1978) Summary reports on determination of mutagenic/<br />

carcinogenic and cytotoxic potential of four chemical compounds to Sherwin Williams<br />

Company, unpublished data cited in EPA IRIS data base<br />

(162) Gaikwad NW, and Bodell WJ (2001) Formation of DNA adducts by microsomal and<br />

peroxidase activation of p-cresol: role of quinone methide in DNA adduct formation. Chem-<br />

Biol Interact 138: 217-229<br />

(163) Hazleton Laboratories America Inc. (1989) Ivett JL. Dominant lethal assay in mice; p-<br />

cresol. June 27, 1989 (at the request of CMA), EPA/OTS0529223<br />

(164) Hazleton Labortories America, Inc. (1989) Seranau SC. Mutagenicity test on para-cresol<br />

Drosophila Melanogaster sex-linked recessive lethal test. February 22, 1989 (at the request<br />

of CMA).<br />

(165) Boutwell RK and Bosch DK (1959) The tumor-promoting action of phenol and related<br />

compounds for mouse skin. Cancer Res 19: 413-424<br />

(166) Hirose M, Inoue T, Asamoto M, Tagawa Y, Ito N (1986) Comparison of the effects of 13<br />

phenolic compounds in induction of proliferative lesions of the forestomach and increase in<br />

the labelling indices of the glandular stomach and urinary bladder of Syrian Golden<br />

Hamsters. Carcinogenesis 7: 1285-1289<br />

(167) Hazleton Laboratories America Inc. (1988) Mutagenicity tests on meta-cresol and paracresol<br />

in the in vitro transformation of BALB/C-3T3 cells assay, June 27, 1988 (at the<br />

request of CMA), EPA/OTS 517694<br />

(168) Bushy Run Centre (1989) Neeper-Bradley TL and Tyl RW. Two-generation reproduction<br />

study of p-cresol (CAS No.106-44-5) administered by gavage to Sprague-Dawley (CD)<br />

rats. Project report 52-512. November 13, 1989. Unpublished data submitted by Bushy Run<br />

Research Center to The American Chemistry Council <strong>Cresol</strong>s Panel, Washington, DC,<br />

EPA/OTS0529224<br />

(169) Bushy Run Research Center/Hazleton Laoratories (1988) Project report 51-509,<br />

Developmental toxicity evaluation of o-, m-, or p-cresol administered by gavage to<br />

Sprague-Dawley (CD) rats, June,1988 (at the request of CMA) EPA/OTS0517695<br />

UNEP PUBLICATIONS 293

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