m-Cresol - ipcs inchem

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OECD SIDS p-CRESOL 4. ECOTOXICITY ID: 106-44-5 DATE: 24.05.2004 07.05.2004 (117) Species : Brassica rapa (Dicotyledon) Endpoint : other: germination and growth rate Exposure period : 4 day(s) Unit : g/l Method : Year : 1989 GLP : No Test substance : other TS: p-cresol, special grade purity (obtained from Wako Pure Chemicals Industries, Ltd.) Method : seeds exposed to test compounds dissolved in distilled water; 3 replicated of 20 seeds Result : Concentr. Germination rate% Growth rate% g/l 1 day 4 days Radicle Hypocotyl 10 0 0 1 0 0 0.1 105.3 100.0 50.9 79.2 Test condition : 24 degrees C; 10 h light, 14 h dark Reliability : (3) invalid Experimental details missing. No control values for germination reported; effect values cannot be related to environmentally relevant conditions 07.05.2004 (117) Species : Brassica campestris var. chinensis (Dicotyledon) Endpoint : other: germination and growth rate Exposure period : 4 day(s) Unit : g/l Method : Year : 1989 GLP : No Test substance : other TS: p-cresol, special grade purity (obtained from Wako Pure Chemicals Industries, Ltd.) Method : seeds exposed to test compounds dissolved in distilled water; 3 replicated of 20 seeds Result : Concentr. Germination rate% Growth rate% g/l 1 day 4 days Radicle Hypocotyl 10 0 0 1 0 0 0.1 71.9 103.9 79.4 72.0 Test condition : 24 degrees C; 10 h light, 14 h dark Reliability : (3) invalid Experimental details missing. No control values for germination reported; effect values cannot be related to environmentally relevant conditions 07.05.2004 (117) Species : Lactuca sativa (Dicotyledon) Endpoint : emergence Exposure period : 3 day(s) Unit : mg/l EC50 : 122 Method : other: Seed germination test Year : 1978 GLP : No Test substance : other TS: p-cresol, no purity reported Method : As described by Reynolds 1975 (Characterization of osmotic restraints on 246 UNEP PUBLICATIONS
OECD SIDS p-CRESOL 4. ECOTOXICITY ID: 106-44-5 DATE: 24.05.2004 lettuce fruit germination. Ann. Bot. 39, 791-796) and 1977 (Comparative effects of aliphatic compounds on inhibition of lettuce fruit germination. Ann. Bot. 41, 637-648) - Lettuce cultivar Great Lakes - Germination temperature 30 °C Result : Result was reported as "1.13 mmol/l" which equals 122 mg/l Reliability : (2) valid with restrictions Basic data given 07.05.2004 (118) 4.6.3 TOXICITY TO SOIL DWELLING ORGANISMS 4.6.4 TOX. TO OTHER NON MAMM. TERR. SPECIES Species : other avian: Agelaius phoeniceus (red-winged blackbird) Endpoint : mortality Exposure period : Unit : mg/kg bw LD50oral : = 96 Method : Year : 1983 GLP : no data Test substance : other TS: p-cresol, no purity reported Test condition : birds pre-conditioned to captivity for 2 to 6 weeks dosed by gavage with solution in propylene glycol or by pellets resp. gelatine capsules Reliability : (2) valid with restrictions Unsuitable test system 07.05.2004 (119) 4.7 BIOLOGICAL EFFECTS MONITORING 4.8 BIOTRANSFORMATION AND KINETICS 4.9 ADDITIONAL REMARKS Memo : Sea urchin test Remark : Strongylocentrotus droebachiensis (sea urchin): static test, 5 degrees C Determined effect endpoints: death, pathology, inhibition of cleavage and differentiation, pigment defects EC50 (96 h): 5 mg/l Test substance : other TS: p-cresol, purity > 98 % as determined by GC (obtained from Merck) Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 07.05.2004 (84) Memo : Tree neoplasms UNEP PUBLICATIONS 247
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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OECD SIDS m-CRESOL 2. PHYSICO-CHEMI
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