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m-Cresol - ipcs inchem

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OECD SIDS<br />

m- / p-CRESOL MIXTURE<br />

5. TOXICITY ID: 15831-10-4<br />

DATE: 24.05.2004<br />

Remark : There are several human case studies reporting the use of<br />

Lysol, a cresol-containing solution, as an abortificant. In<br />

addition, intravaginal application of Lysol produces<br />

extensive hemolysis, erosion of blood vessels, kidney<br />

tubular damage, liver necrosis and death.<br />

Reliability : (4) not assignable<br />

16.01.2003 (112) (113)<br />

Remark : The probable oral lethal dose for humans is 50-500 mg/kg bw<br />

Reliability : (2) valid with restrictions<br />

16.01.2003 (114)<br />

5.11 ADDITIONAL REMARKS<br />

Type : other<br />

Remark : 0.2% Formocresol, containing 35% cresol and 19%<br />

formaldehyde, causes the cell death of 50% of the treated<br />

Hela cells within 4 hours.<br />

Reliability : (4) not assignable<br />

16.01.2003 (115)<br />

370<br />

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