m-Cresol - ipcs inchem

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OECD SIDS m- / p-CRESOL MIXTURE 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 15831-10-4 DATE: 24.05.2004 No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 12.05.2004 (35) Type : anaerobic Inoculum : other: shallow anaerobic alluvial sand aquifer Deg. product : yes Method : other: measured Year : 1986 GLP : no Test substance : other TS: m-cresol, no purity reported (obtained from Aldrich Chemical Co.) Deg. products : 74-82-8 200-812-7 methane Method : 2 sampling sites: 1 methanogenic, 1 sulfate-reducing both aquifers receive leachate from a municipal landfill Result : lag time 43 days under sulfate-reducing and 46-90 days under methanogenic conditions, no data for complete degradation given Test condition : test medium: 50 g [wet weight] of aquifer solids and 50 ml of groundwater incubation at room temperature in the dark, quadruplicates preincubation 5 days, addition of 150 to 200 µM test substance Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 12.05.2004 (36) Type : anaerobic Inoculum : other: undefined methanogenic consortia from river sediment Concentration : 54 mg/l related to Test substance related to Deg. product : yes Method : other: measured Year : 1989 GLP : no Test substance : other TS: m-cresol, no purity reported Deg. products : 74-82-8 200-812-7 methane Method : black anoxic mud collected from a river inoculated in a mineral medium (10% w/v) Result : non-acclimated consortia: turnover rate 1.10 µmol/day/g sediment dw (lag-phase 16 d) acclimated consortia: turnover rate 2.37 µmol/day/g sediment dw (lag-phase 0 d, based on a 24-days-incubation period), the CH4 production was 96 % of the theoretically possible yield Test condition : incubation at 28 degrees C in the dark cultures were refed with 60 mg/l test substance every 2-4 w for a total of 18 months Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 12.05.2004 (37) Type : aerobic Inoculum : Concentration : 10 mg/l related to Test substance 322 UNEP PUBLICATIONS
OECD SIDS m- / p-CRESOL MIXTURE 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 15831-10-4 DATE: 24.05.2004 related to Contact time : 3 day(s) Degradation : 26 - 100 (±) % after 3 day(s) Result : Deg. product : Method : other: cultivation method Year : 1987 GLP : no data Test substance : other TS: m-cresol, no purity reported in abstract Result : biodegradation in river water = 100 % biodegradation in sea water = 26 % The authors assume the compound to be moderately to easily biodegradable Reliability : (4) not assignable Japanese reference with short abstract in English 12.05.2004 (38) Type : anaerobic Inoculum : other: microcosm containing aquifer and ground water Concentration : 18 mg/l related to Test substance related to Deg. product : yes Method : other: measured Year : 1989 GLP : no data Test substance : other TS: m-cresol, no purity reported Deg. products : 74-82-8 200-812-7 methane Result : lag time 110 days, disappearance after approx. 225 d (values taken from a graphics) Test condition : methanogenic conditions in a microcosm Reliability : (3) invalid Insufficient documentation 12.05.2004 (39) Type : anaerobic Inoculum : other: anoxic aquifer Concentration : 300 µmol/l related to Test substance related to Deg. product : Method : other: measured Year : 1990 GLP : no data Test substance : other TS: m-cresol, no purity reported Method : anoxic aquifer slurries held under sulfate- and nitrate-reducing conditions Result : m-cresol was largely degraded in less than 6 d degradation dependant on sulfate, inhibited by 1.0 mM molybdate, not influenced by bromoethanesulfonic acid Reliability : (4) not assignable only abstract available 12.05.2004 (40) 3.6 BOD5, COD OR BOD5/COD RATIO UNEP PUBLICATIONS 323
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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