m-Cresol - ipcs inchem

OECD SIDS
p-CRESOL
4. ECOTOXICITY ID: 106-44-5
DATE: 24.05.2004
Reliability : (2) valid with restrictions
Study comparable to national guideline
Flag : Critical study for SIDS endpoint
07.05.2004 (92) (93)
Species : other aquatic worm: Dugesia tigrina
Endpoint : other: mortality, reporduction and
Exposure period : 80 day(s)
Unit : mg/l
NOEC : 1
Analytical monitoring : No
Method : other: see test conditions
Year : 1987
GLP : No
Test substance : other TS: p-cresol, no purity reported
Method : Worms 18-24 days old, length 11-12 mm;
In each flask 10 test organisms (5 each cut into two parts);
regeneration of the lacking parts occurred within 10 days;
the worms were fed in the next 10 days and reached their
original length 20 days after cutting; then animals cut
again, altogether 4 times
Result : LC50 = 11.08 mg/l after 10 days
LC10 = 2.0 mg/l after 80 days (4 generations)
LC20 = 4.0 mg/l after 80 days (4 generations)
Test condition : 20 degrees C; medium according ISO/TC 147/SC 5/GT 3 N. 38
Reliability : (2) valid with restrictions
No standard test procedure, but in accordance with generally
accepted scientific standards and described in sufficient
detail
07.05.2004 (116)
4.6.1 TOXICITY TO SEDIMENT DWELLING ORGANISMS
4.6.2 TOXICITY TO TERRESTRIAL PLANTS
Species : Raphanus sativus (Dicotyledon)
Endpoint : other: germination and growth rate
Exposure period : 4 day(s)
Unit : g/l
Method :
Year : 1989
GLP : No
Test substance : other TS: p-cresol, special grade purity (obtained from Wako Pure
Chemicals Industries, Ltd.)
Method : Seeds exposed to test compounds dissolved in distilled
water; 3 replicated of 20 seeds
Result : Concentr. Germination rate% Growth rate%
g/l 1 day 4 days Radicle Hypocotyl
10 0 0
1 0 0
0.1 70 88.5 65.1 75.6
Test condition : 24 degrees C; 10 h light, 14 h dark
Reliability : (3) invalid
Experimental details missing. No control values for germination reported;
effect values cannot be related to environmentally relevant conditions
UNEP PUBLICATIONS 245