m-Cresol - ipcs inchem

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OECD SIDS p-CRESOL 4. ECOTOXICITY ID: 106-44-5 DATE: 24.05.2004 Unit : mg/l LC50 : = 1.4 Analytical monitoring : no data Method : other: according to the method described by Parkhurst et al. 1977 Year : 1979 GLP : no Test substance : other TS: p-cresol, no purity reported Method : Parkhurst BR, Gehrs CW, Rubin IB (1977): Proceedings of ASTM 2nd Annual Symposium on Aquatic Toxicology, 122-130 Test condition : Daphnia magna used in the test were adults. 100-ml test beakers were filled with 80 ml test solution and 4 daphnia. All the tests were run in triplicate. Temperature during the test: 25 +/- 0.5°C 12h light/dark cycle Test solution was prepared with filtered spring water (pH 7.8 alkalinity mg/l, hardness 140 mg/l) Control beakers were used 48h-EC50 values were obtained by PROBIT Test substance : The test substance was obtained from an effluent Reliability : (3) invalid Methodological deficiencies (method description is in the other reference from the same author). Age of daphnias used in the test is not clearly specified: test daphnias were "adults" (in the OECD guideline a 24h-old daphnia is suggested); temperature during the test was 25°C (in the guideline is suggested: 18-22°C); 12 daphnia were used for each test concentration (in the guideline 40 daphnias are suggested) 07.05.2004 (97) Type : static Species : Daphnia sp. (Crustacea) Exposure period : 48 hour(s) Unit : mg/l TT : = 12 Analytical monitoring : no Method : Year : 1959 GLP : no Test substance : other TS: p-cresol, no purity reported Method : test organisms were reared from daphnids collected in surface water Test condition : river water, pH 7.5 Reliability : (3) invalid Experimental details missing. Study does not follow any guideline, concentrations tested were not reported, no information about the application method of the test substance is given. Neither O2/pH monitoring nor analytical monitoring were applied 07.05.2004 (98) 4.3 TOXICITY TO AQUATIC PLANTS E.G. ALGAE 234 Species : Scenedesmus subspicatus (Algae) Endpoint : other: biomass and growth Exposure period : 48 hour(s) Unit : mg/l Limit test : Analytical monitoring : no Method : other: DIN 38412, part 9 Year : 1990 UNEP PUBLICATIONS
OECD SIDS p-CRESOL 4. ECOTOXICITY ID: 106-44-5 DATE: 24.05.2004 GLP : no Test substance : other TS: p-cresol, no purity reported Result : EbC10 = 2.3 mg/l ErC10 = 4.6 mg/l EbC50 = 7.8 mg/l ErC50 = 21 mg/l Test condition : 24 +- 1 degrees C; TS concentration 0.8 - 100 mg/l, dilution series 1:2 preliminary culture 10E5 cells/,l irradiance 17.0 W/m2 Reliability : (2) valid with restrictions Test procedure according to national guideline Flag : Critical study for SIDS endpoint 07.05.2004 (99) Species : Chlorella pyrenoidosa (Algae) Endpoint : other: chlorophyll content Exposure period : 72 hour(s) Unit : mg/l EC0 : < 50 EC50 : 116 EC100 : 250 Limit test : no Analytical monitoring : no Method : Year : 1968 GLP : no Test substance : other TS: p-cresol, no purity reported Result : Complete destruction of chlorophyll at 1000 mg/l after 1 day. EC50 was not reported in the study, but it can be taken from the graph Test condition : TEST ORGANISMS - Strain: Emerson strain - Test temperature: 25 +- 1 degrees C - pH: 7.0 - Photoperiod: continuous illumination TEST PARAMETER: chlorophyll Reliability : (2) valid with restrictions Study in accordance with generally accepted scientific standards and described in sufficient detail 12.05.2004 (100) Species : other aquatic plant: Potamogeton coloratus Endpoint : other: photosynthesis Exposure period : 21 day(s) Unit : mg/l NOEC : < .22 LOEC : = .22 EC50 : > 1.08 Limit test : Analytical monitoring : no Method : Year : 1983 GLP : no Test substance : other TS: p-cresol, no purity reported Method : simulation of running water under summer climate conditions Test condition : water hardness: 9° dH; conductivity: 300 µS; pH 7.8 Reliability : (3) invalid Methodological deficiencies. Most test conditions not indicated. No UNEP PUBLICATIONS 235
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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OECD SIDS m-CRESOL 2. PHYSICO-CHEMI
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OECD SIDS m-CRESOL 3. ENVIRONMENTAL
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OECD SIDS m-CRESOL 4. ECOTOXICITY I
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OECD SIDS p-CRESOL 6. REFERENCES ID
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OECD SIDS m- / p-CRESOL MIXTURE I U
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OECD SIDS m- / p-CRESOL MIXTURE 1.
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