m-Cresol - ipcs inchem

OECD SIDS
m-CRESOL
3. ENVIRONMENTAL FATE AND PATHWAYS ID: 108-39-4
DATE: 24.05.2004
%
Deg. product :
Method : OECD Guide-line 301 D "Ready Biodegradability: Closed Bottle Test"
Year : 1988
GLP : no
Test substance : other TS: m-cresol pure
Remark : In two further tested concentrations (8 and 24 mg/l) the dissolved oxygen
was completely emaciated within 7 days (concentration of control
substance 8 and 24 mg/l for tests with 8 and 24 mg/l of test substance,
respectively. Also i n these control experiments, oxygen was emaciated).
Result : Compared to the test with 0.8 mg/l the extent of degradation is lesser at 2.4
mg/l presumably due to the fact that most of the oxygen was used up at the
high test substance concentration (10-day criteria met in only one of the
two replicates)
Test condition : Inoculum / test organism
- Type of sludge: activated sludge
- Source: treatment plant, receiving domestic sewage
- Sampling site: Odenthal
Concentration of control substance: 2.4 mg/l
Analytical parameter: Oxygen consumption
Test temperature: 20 degrees C
Test was performed in two paralleles.
Reliability : (2) valid with restrictions
Guideline Study
11.05.2004 (33)
Type : aerobic
Inoculum : activated sludge, domestic
Concentration : 100 mg/l related to Test substance
related to
Contact time :
Degradation : 80 - 95 (±) % after 40 day(s)
Result :
Deg. product :
Method : other: comparable to OECD Guide-line 301 C
Year : 1981
GLP : no
Test substance : other TS: m-cresol, purity > 99 %
Method : Initial sludge concentration: 30 mg d.w./l; aniline as
reference compound
Remark : Incubation period: 20-40 days; no oxygen uptake curve given;
degradation of reference substance aniline >/= 60 % within 28 days
Result : The oxygen uptake curves are not reported. However, the authors state
that all test compounds revealed the lag phase, biodegradation phase and
the plateau region within a period of 10 days, indicating that the 10-day
window criteria is met.
First order biodegradation constant (hr-1): ln k = -5.77
maximum specific substrate uptake rate per unit biomass km = 17.3 / day
(Aniline 16.1, Phenol 16.9).
m-Cresol is slightly better biodegradable than phenol and aniline.
Test condition : Inoculum /test organism
- Type of sludge: activated
- Source: municipal treatment plant, receiving predominantly domestic
sewage
- Initial cell concentration: 30 mg/l
Test system
- Culturing apparatus: Sapromat
- Closed vessels used: yes
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