m-Cresol - ipcs inchem

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OECD SIDS m-CRESOL 5. TOXICITY ID: 108-39-4 DATE: 24.05.2004 Type : other: LD Value : ca. 120 mg/kg bw Species : cat Strain : Sex : no data Number of animals : Vehicle : no data Doses : Route of admin. : s.c. Exposure time : Method : other: no data Year : 1905 GLP : no Test substance : other TS: no data Reliability : (4) not assignable unusual application route 18.09.2002 (125) Type : other: LD Value : = 300 mg/kg bw Species : guinea pig Strain : Sex : Number of animals : Vehicle : no data Doses : Route of admin. : s.c. Exposure time : Reliability : (4) not assignable unusual application route 18.09.2002 (124) Type : other: LD Value : = 250 mg/kg bw Species : other: frog Strain : Sex : no data Number of animals : 1 Vehicle : water Doses : Route of admin. : s.c. Exposure time : Method : other: no data Year : 1905 GLP : no Test substance : other TS: no data Reliability : (4) not assignable unusual application route 05.02.2004 (125) Type : other: LD Value : Species : rabbit Strain : Sex : Number of animals : 1 Vehicle : other: water Doses : 130 UNEP PUBLICATIONS
OECD SIDS m-CRESOL 5. TOXICITY ID: 108-39-4 DATE: 24.05.2004 Route of admin. : i.v. Exposure time : Method : other: intravenous injection to 1 rabbit per dose of an 0.5 % aqueous solution, 4 doses, time until death was recorded Year : 1944 GLP : no data Test substance : other TS: purity no data Remark : hours until death: 120 and 180 mg/kg: no death; 280 mg/kg: 15 hours; 420 mg/kg: 7 hours Reliability : (4) not assignable unusual application route 18.09.2002 (118) Type : other: LD Value : = 150 mg/kg bw Species : dog Strain : Sex : no data Number of animals : Vehicle : other: no data Doses : Route of admin. : i.v. Exposure time : Method : other: no data Year : GLP : no Test substance : other TS: no data Reliability : (4) not assignable unusual application route 18.09.2002 (124) 5.2.1 SKIN IRRITATION Species : rabbit Concentration : .5 other: ml Exposure : Semiocclusive Exposure time : 4 hour(s) Number of animals : 6 Vehicle : PDII : Result : corrosive Classification : Method : other: see freetext ME Year : 1977 GLP : no data Test substance : other TS: m-cresol, not specified further Method : TS applied to the clipped backs or flanks of the rabbits. The material was covered by a surgical gauze two layers thick, gauze patches were held in place with strips of Elastoplast tape for 4 hours. After 4 hrs the patches were carefully removed and the test areas were evaluated for visible tissue destruction. evaluation criterias: When visible tissue destruction occurred in at least 2/6 rabbits, the test materials were classified as corrosive (no further details given). Reliability : (2) valid with restrictions Limited documentation Flag : Critical study for SIDS endpoint UNEP PUBLICATIONS 131
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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OECD SIDS m-CRESOL 2. PHYSICO-CHEMI
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OECD SIDS m-CRESOL 3. ENVIRONMENTAL
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OECD SIDS p-CRESOL 1. GENERAL INFOR
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OECD SIDS p-CRESOL 1. GENERAL INFOR
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OECD SIDS p-CRESOL 2. PHYSICO-CHEMI
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OECD SIDS p-CRESOL 4. ECOTOXICITY I
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OECD SIDS m- / p-CRESOL MIXTURE I U
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OECD SIDS m- / p-CRESOL MIXTURE 1.
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m-Cresol - ipcs inchem

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