m-Cresol - ipcs inchem

More documents

Recommendations

Info

OECD SIDS p-CRESOL 4. ECOTOXICITY ID: 106-44-5 DATE: 24.05.2004 Remark : p-cresol (1.5% v/v) showed a toxicity rating from 3-4 (0 = no injury, 5 = complete kill within 14d) in tomato crown gall tumors incited by Agrobacterium tumefaciens Test substance : other TS: p-cresol, no purity reported Reliability : (3) invalid unusual endpoint 07.05.2004 (120) 248 UNEP PUBLICATIONS
OECD SIDS p-CRESOL 5. TOXICITY ID: 106-44-5 DATE: 24.05.2004 5.0 TOXICOKINETICS, METABOLISM AND DISTRIBUTION In Vitro/in vivo : In vitro Type : Absorption Species : other: human skin Number of animals Males : Females : Doses Males : Females : Vehicle : Water Route of administration : dermal Exposure time : 250 minute(s) Product type guidance : Decision on results on acute tox. tests : Adverse effects on prolonged exposure : Half-lives : 1 st : 2 nd : 3 rd : Toxic behaviour : Deg. product : Method : other: see freetext ME Year : 1977 GLP : no data Test substance : other TS: p-cresol, purity: reagent grade Method : The permeability of p-Cresol was measured across 2.5 cm2 epidermal membranes from human abdominal skin. The membranes were supported in a glass cell and the amount of p-Cresol passing to the receptor vessel measured spectrophotometrically. Each test was conducted at least in duplicate and at 25 Degree Celsius Result : The permeability coefficient of p-Cresol was 2.92 x10 (exp)-4 cm/min and the lag time for a 0.4%w/v solution was 16 min. The threshold concentration for damage i.e. the aqueous concentration at which the permeability coefficient began to increase was 8.85 %w/v. Reliability : (2) valid with restrictions in vitro investigation Flag : Critical study for SIDS endpoint 06.02.2004 (121) In Vitro/in vivo : In vivo Type : Toxicokinetics Species : Rabbit Number of animals Males : Females : Doses Males : Females : Vehicle : other: sodium hydroxycarbonate Route of administration : gavage Exposure time : Product type guidance : Decision on results on acute tox. tests : Adverse effects on prolonged exposure : Half-lives : 1 st : 2 nd : 3 rd : UNEP PUBLICATIONS 249
Page 1 and 2:
OECD SIDS m- / p-CRESOL FOREOWRD IN
Page 3 and 4:
OECD SIDS m- / p-CRESOL 11. Comment
Page 5 and 6:
OECD SIDS m- / p-CRESOL of mice. In
Page 7 and 8:
OECD SIDS m- / p-CRESOL SIDS Initia
Page 9 and 10:
OECD SIDS m- / p-CRESOL Table 3: Es
Page 11 and 12:
OECD SIDS m- / p-CRESOL m-cresol an
Page 13 and 14:
OECD SIDS m- / p-CRESOL extensive s
Page 15 and 16:
OECD SIDS m- / p-CRESOL et al. 1993
Page 17 and 18:
OECD SIDS m- / p-CRESOL study in wh
Page 19 and 20:
OECD SIDS m- / p-CRESOL Conclusion:
Page 21 and 22:
OECD SIDS m- / p-CRESOL Table 5: m-
Page 23 and 24:
OECD SIDS m- / p-CRESOL ≥300 ppm,
Page 25 and 26:
OECD SIDS m- / p-CRESOL Atrophy and
Page 27 and 28:
OECD SIDS m- / p-CRESOL p-Cresol p-
Page 29 and 30:
OECD SIDS m- / p-CRESOL 3.1.7 Carci
Page 31 and 32:
OECD SIDS m- / p-CRESOL weights wer
Page 33 and 34:
OECD SIDS m- / p-CRESOL drowsiness,
Page 35 and 36:
OECD SIDS m- / p-CRESOL and reduced
Page 37 and 38:
OECD SIDS m- / p-CRESOL The most se
Page 39 and 40:
OECD SIDS m- / p-CRESOL Table 14: T
Page 41 and 42:
OECD SIDS m- / p-CRESOL Table 15: T
Page 43 and 44:
OECD SIDS m- / p-CRESOL 5 RECOMMEND
Page 45 and 46:
OECD SIDS m- / p-CRESOL BRRC (Bushy
Page 47 and 48:
OECD SIDS m- / p-CRESOL Hamster Ova
Page 49 and 50:
OECD SIDS m- / p-CRESOL Nobel W, Ma
Page 51 and 52:
OECD SIDS m- / p-CRESOL Vernot EH,
Page 53 and 54:
OECD SIDS m- / p-CRESOL Available P
Page 55 and 56:
OECD SIDS m- / p-CRESOL √ informa
Page 57 and 58:
OECD SIDS m-CRESOL 1. GENERAL INFOR
Page 59 and 60:
Page 61 and 62:
Page 63 and 64:
Page 65 and 66:
Page 67 and 68:
OECD SIDS m-CRESOL 2. PHYSICO-CHEMI
Page 69 and 70:
Page 71 and 72:
Page 73 and 74:
OECD SIDS m-CRESOL 3. ENVIRONMENTAL
Page 75 and 76:
Page 77 and 78:
Page 79 and 80:
Page 81 and 82:
Page 83 and 84:
Page 85 and 86:
Page 87 and 88:
Page 89 and 90:
Page 91 and 92:
OECD SIDS m-CRESOL 4. ECOTOXICITY I
Page 93 and 94:
Page 95 and 96:
Page 97 and 98:
Page 99 and 100:
Page 101 and 102:
Page 103 and 104:
Page 105 and 106:
Page 107 and 108:
Page 109 and 110:
Page 111 and 112:
Page 113 and 114:
Page 115 and 116:
Page 117 and 118:
Page 119 and 120:
OECD SIDS m-CRESOL 5. TOXICITY ID:
Page 121 and 122:
Page 123 and 124:
Page 125 and 126:
Page 127 and 128:
Page 129 and 130:
Page 131 and 132:
Page 133 and 134:
Page 135 and 136:
Page 137 and 138:
Page 139 and 140:
Page 141 and 142:
Page 143 and 144:
Page 145 and 146:
Page 147 and 148:
Page 149 and 150:
Page 151 and 152:
Page 153 and 154:
Page 155 and 156:
Page 157 and 158:
Page 159 and 160:
Page 161 and 162:
Page 163 and 164:
OECD SIDS m-CRESOL 6. REFERENCES ID
Page 165 and 166:
Page 167 and 168:
Page 169 and 170:
Page 171 and 172:
Page 173 and 174:
Page 175 and 176:
OECD SIDS p-CRESOL 1. GENERAL INFOR
Page 177 and 178:
Page 179 and 180:
Page 181 and 182:
Page 183 and 184:
Page 185 and 186:
OECD SIDS p-CRESOL 2. PHYSICO-CHEMI
Page 187 and 188:
Page 189 and 190:
Page 191 and 192:
Page 193 and 194:
Page 195 and 196:
Page 197 and 198: OECD SIDS p-CRESOL 3. ENVIRONMENTAL
Page 223 and 224: OECD SIDS p-CRESOL 4. ECOTOXICITY I
Page 247: OECD SIDS p-CRESOL 4. ECOTOXICITY I
Page 251 and 252: OECD SIDS p-CRESOL 5. TOXICITY ID:
Page 287 and 288: OECD SIDS p-CRESOL 6. REFERENCES ID
Page 295 and 296: OECD SIDS m- / p-CRESOL MIXTURE I U
Page 297 and 298: OECD SIDS m- / p-CRESOL MIXTURE 1.
Page 299 and 300:
OECD SIDS m- / p-CRESOL MIXTURE 1.
Page 301 and 302:
Page 303 and 304:
Page 305 and 306:
Page 307 and 308:
Page 309 and 310:
Page 311 and 312:
Page 313 and 314:
Page 315 and 316:
Page 317 and 318:
Page 319 and 320:
Page 321 and 322:
Page 323 and 324:
Page 325 and 326:
Page 327 and 328:
Page 329 and 330:
Page 331 and 332:
Page 333 and 334:
Page 335 and 336:
Page 337 and 338:
Page 339 and 340:
Page 341 and 342:
Page 343 and 344:
Page 345 and 346:
Page 347 and 348:
Page 349 and 350:
Page 351 and 352:
Page 353 and 354:
Page 355 and 356:
Page 357 and 358:
Page 359 and 360:
Page 361 and 362:
Page 363 and 364:
Page 365 and 366:
Page 367 and 368:
Page 369 and 370:
Page 371 and 372:
Page 373 and 374:
Page 375 and 376:
Page 377:
show all

m-Cresol - ipcs inchem

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?