m-Cresol - ipcs inchem

OECD SIDS
m- / p-CRESOL MIXTURE
4. ECOTOXICITY ID: 15831-10-4
DATE: 24.05.2004
4.1 ACUTE/PROLONGED TOXICITY TO FISH
326
Type : flow through
Species : Oncorhynchus mykiss (Fish, fresh water)
Exposure period : 96 hour(s)
Unit : mg/l
LC50 : 8.9
Limit test :
Analytical monitoring : yes
Method : other: US EPA, Methods for acute toxicity tests with fish,
macroinvertebrates, and amphibians. Nat. Environm. Res. Center, Corvallis
(1974)
Year : 1980
GLP : no data
Test substance : other TS: m-cresol, no purity reported
Method : Mean length/mean weight of fish: 7.9 cm/6.0 g
Result : sublethal effects: hyperactivity, rapid operculation,
sensitive to disturbance and gathering at the surface
Test condition : DILUTION WATER
- Source: well water
- Hardness: 707.3 mg CaCO3/l
- Conductance: 1212.3 µmhos/cm at 25 degrees C
TEST SYSTEM
- Concentrations: 1:2 dilution series
- Number of replicates: 2
- fish per replicate: 10
- Test temperature: 14 degrees C
- Dissolved oxygen: 6.5 mg/l (84.5% of saturation)
- pH: 8.1
- Photoperiod: 16 h light, 8 h dark
Reliability : (1) valid without restriction
Test procedure comparable to standard method and in
accordance with generally accepted scientific standards;
detailed documentation of test procedure and test conditions
Flag : Critical study for SIDS endpoint
12.05.2004 (42)
Type : flow through
Species : Pimephales promelas (Fish, fresh water)
Exposure period : 96 hour(s)
Unit : mg/l
LC50 : 55.9
Limit test :
Analytical monitoring : yes
Method : other: US EPA, Methods for acute toxicity tests with fish,
macroinvertebrates, and amphibians. Nat. Environm. Res. Center, Corvallis
(1974)
Year : 1980
GLP : no data
Test substance : other TS: m-cresol
Method : Mean length/mean weight of fish: 4.9 cm/1.6 g
Result : sublethal effects: loss of equilibrium, erratic swiming and
twitching at a test substance concentration of 49.8 mg/l
Test condition : DILUTION WATER
- Source: well water
- Hardness: 707.3 mg CaCO3/l
- Conductance: 1212.3 µmhos/cm at 25 degrees C
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