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m-Cresol - ipcs inchem

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OECD SIDS<br />

p-CRESOL<br />

4. ECOTOXICITY ID: 106-44-5<br />

DATE: 24.05.2004<br />

Test substance : other TS: p-cresol, no purity reported<br />

Remark : Although it is suggested that Microtox may lack reproducibility due to<br />

variations in bacterial cell suspensions [Bitton G (1983) Bacterial and<br />

Biochemical Tests for Assessing Chemical Toxicity in the Aquatic<br />

Environment: A Review. Crit Rev Environ Control 13: 51 -67], no<br />

information is supplied on the source of the lyophilized bacteria, their age,<br />

duration of reconstitution and other important parameters<br />

Test condition : 15 degrees C<br />

Reliability : (3) invalid<br />

Unsuitable test system. Organisms are of marine origin. Method is not<br />

appropriate for the hazard assessment of chemicals<br />

07.05.2004 (114)<br />

Type : Aquatic<br />

Species : other bacteria: Rhizobium melioti<br />

Exposure period : 30 minute(s)<br />

Unit : mg/l<br />

IC50 : = 7.1 calculated<br />

Analytical monitoring : No<br />

Method :<br />

Year : 1997<br />

GLP : No<br />

Test substance : other TS: p-cresol, no purity reported<br />

Remark : endpoint: inhibition of reduction reaction of a dye<br />

(3-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium<br />

bromide; MTT)<br />

Reliability : (3) invalid<br />

unusual endpoint<br />

07.05.2004 (115)<br />

Type : Aquatic<br />

Species : other bacteria: Pseudomonas Stamm Berlin 33/2<br />

Exposure period :<br />

Unit : mg/l<br />

EC0 : = 80<br />

Analytical monitoring : No<br />

Method :<br />

Year : 1982<br />

GLP : No<br />

Test substance : other TS: p-cresol, no purity reported<br />

Remark : Effect endpoint: inhibition of cell multiplication<br />

Reliability : (4) not assignable<br />

Experimental details missing<br />

12.05.2004 (87)<br />

4.5.1 CHRONIC TOXICITY TO FISH<br />

Species : Pimephales promelas (Fish, fresh water)<br />

Endpoint : other: growth<br />

Exposure period : 32 day(s)<br />

Unit : mg/l<br />

NOEC : 1.35<br />

LOEC : 2.57<br />

Analytical monitoring : no data<br />

Method : other: Early life stage test<br />

Year : 1984<br />

GLP : No<br />

UNEP PUBLICATIONS 243

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