m-Cresol - ipcs inchem

OECD SIDS
m-CRESOL
4. ECOTOXICITY ID: 108-39-4
DATE: 24.05.2004
Remark : effect: reduction of bioluminescence
Secondary literature. Not enough information supplied for assessment.
Although the author suggests that Microtox may lack reproductibility due to
variations in bacterial cell suspensions, no information is supplied on the
maintenance of the lyophilized bacteria, their age, duration of reconstitution
and other important parameters.
Reliability : (3) invalid
Unsuitable test system. Organisms are of marine origin. Method is not
appropriate for the hazard assessment of chemicals.
07.05.2004 (89)
Type : aquatic
Species : Photobacterium phosphoreum (Bacteria)
Exposure period : 15 minute(s)
Unit : mg/l
EC50 : 8
Analytical monitoring : no
Method : other: Microtox assay
Year : 1987
GLP : no
Test substance : other TS: m-cresol, analytical grade (either from Merck or EGA Chemie)
Remark : Not enough information supplied for assessment of the test used (Test
done according to Beckman manual). Although it is suggested that
Microtox may lack reproducibility due to variations in bacterial cell
suspensions [Bitton G (1983) Bacterial and Biochemical Tests for
Assessing Chemical Toxicity in the Aquatic Environment: A Review. Crit
Rev Environ Control 13: 51 -67], no information is supplied on the
maintenance of the lyophilized bacteria, their age, duration of reconstitution
and other important parameters.
Reliability : (3) invalid
Unsuitable test system. Organisms are of marine origin. Method is not
appropriate for the hazard assessment of chemicals.
07.05.2004 (90)
Type : aquatic
Species : other bacteria: Photobacterium (Vibrio) fischeri (marine)
Exposure period : 5 minute(s)
Unit : mg/l
EC50 : 8.2
Analytical monitoring : no
Method : other: Microtox assay
Year : 1981
GLP : no
Test substance : other TS: m-cresol, no purity reported
Remark : Although it is suggested that Microtox may lack reproducibility due to
variations in bacterial cell suspensions [Bitton G (1983) Bacterial and
Biochemical Tests for Assessing Chemical Toxicity in the Aquatic
Environment: A Review. Crit Rev Environ Control 13: 51 -67], no
information is supplied on the maintenance of the lyophilized bacteria, their
age, duration of reconstitution and other important parameters. In contrast
to Bulich [Bulich AA (1977), Aquatic Toxicology: Second conference ASTM
STP 667, American Society for Testing of Materials, Philadelphia, pp 98 -
106], pH not buffered.
Test condition : 15 degrees C
Reliability : (3) invalid
Unsuitable test system. Organisms are of marine origin. Method is not
appropriate for the hazard assessment of chemicals.
07.05.2004 (91)
UNEP PUBLICATIONS 109