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m-Cresol - ipcs inchem

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OECD SIDS<br />

m- / p-CRESOL MIXTURE<br />

4. ECOTOXICITY ID: 15831-10-4<br />

DATE: 24.05.2004<br />

Year : 1985<br />

GLP : no<br />

Test substance : other TS: m-cresol, purity 99.5 %<br />

Method : 6 different pure bacteria cultures: 3 isolated from a<br />

laboratory activated sludge, 2 from activated sludge from a<br />

municipal plant receiving some industry wastewater, and 1<br />

from a lake sediment<br />

Effect: 50 % resazurin reduction (determination of<br />

dehydrogenase activity)<br />

Result : from laboratory sludges: EC50 = >500, 225, and 410 mg/l<br />

from activated sludges: EC50 = 360 and >500 mg/l<br />

from lake sediment: EC50 = >500 mg/l<br />

Test condition : 21 degrees C; incubation 30-60 min<br />

Test substance : purity 99.5%<br />

Reliability : (2) valid with restrictions<br />

No standard test procedure, but in accordance with generally<br />

accepted scientific standards and described in sufficient<br />

detail<br />

12.05.2004 (71)<br />

Type : aquatic<br />

Species : other bacteria: Aerobic heterotrophic<br />

Exposure period : 49 hour(s)<br />

Unit : mg/l<br />

IC 50 : 440<br />

Analytical monitoring : no<br />

Method :<br />

Year : 1991<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : culture obtained from mixed liquor of a treatment plant<br />

Remark : Effect: inhibition of respiration; prolonged incubation<br />

compared with ISO 8192<br />

Test condition : 25 and 35 degrees C<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

sufficient documentation<br />

12.05.2004 (72)<br />

Type : aquatic<br />

Species : other bacteria: Methanogenic bacteria<br />

Exposure period : 96 hour(s)<br />

Unit : mg/l<br />

IC 50 : 890<br />

Analytical monitoring : no<br />

Method : other: Owen, W.F.: Bioassay for Monitoring Biochemical Methane Potential<br />

and Anaerobic Toxicity. Water Res. 13, 485 (1979)<br />

Year : 1991<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Remark : Effect: inhibition of gas production<br />

Test condition : 35 degrees C<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

sufficient documentation<br />

12.05.2004 (72)<br />

340<br />

UNEP PUBLICATIONS

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