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m-Cresol - ipcs inchem

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OECD SIDS<br />

m- / p-CRESOL MIXTURE<br />

4. ECOTOXICITY ID: 15831-10-4<br />

DATE: 24.05.2004<br />

12.05.2004 (61)<br />

4.5.1 CHRONIC TOXICITY TO FISH<br />

4.5.2 CHRONIC TOXICITY TO AQUATIC INVERTEBRATES<br />

4.6.1 TOXICITY TO SEDIMENT DWELLING ORGANISMS<br />

4.6.2 TOXICITY TO TERRESTRIAL PLANTS<br />

Species : other terrestrial plant: Lactuca sativa Ravel R2<br />

Endpoint : growth<br />

Exposure period : 14 day(s)<br />

Unit : mg/kg soil dw<br />

EC50 : 96<br />

Method : OECD Guide-line 208 "Terrestrial Plants, Growth Test"<br />

Year : 1993<br />

GLP : no data<br />

Test substance : other TS: m-cresol, purity >= 95 %<br />

Method : analytical monitoring at start and end of test<br />

Result : EC50 based on nominal concentration; for most of the<br />

examined<br />

phenols (including m-cresol) applied concentrations dropped<br />

to < 20% of the nominal values<br />

Reliability : (2) valid with restrictions<br />

Guideline study; applied test concentrations not stable<br />

during the test period<br />

Flag : Critical study for SIDS endpoint<br />

12.05.2004 (88)<br />

Species : other terrestrial plant: Lactuca sativa Ravel R2<br />

Endpoint : growth<br />

Exposure period : 16 day(s)<br />

Unit : mg/l<br />

EC50 : 50<br />

Method :<br />

Year : 1993<br />

GLP : no data<br />

Test substance : other TS: m-cresol, purity >= 95 %<br />

Method : semistatic test in nutrient solution, renewed 3 times/week<br />

nutrient solution as described in Steiner, A.A.: Soilless<br />

culture. Proceedings, Sixth Colloqium of the International<br />

Potash Institute, Florence, Italy, 324-341 (1968);<br />

analytical monitoring of TS at start and end of exposure and<br />

before renewal of test solution<br />

Result : EC50 based on nominal concentration; TS concentration before<br />

renewal of test solution > 50% of initial concentration<br />

Reliability : (3) invalid<br />

unsuitable test system<br />

11.02.2003 (88)<br />

Species : Raphanus sativus (Dicotyledon)<br />

Endpoint : other: germination and growth rate<br />

348<br />

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