m-Cresol - ipcs inchem

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OECD SIDS m-CRESOL 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 108-39-4 DATE: 24.05.2004 Inoculum : anaerobic sludge Deg. product : yes Method : Year : 1981 GLP : no Test substance : other TS: m-cresol, no purity reported Deg. products : 74-82-8 200-812-7 methane Method : primary anaerobic sludge from 12 treatment plants receiving mainly domestic wastewater were diluted to 10 % in a mineral salts medium, test substance concentration: 30 mg/l; secondary anaerobic sludge from 2 treatment plants diluted to 10 % in a mineral salts medium, test substance: 50 mg/l; incubation for 8 weeks; triplicate samples Result : primary sludges: no degradation was observed in 4 sludges; degradation ranged from 55 to 103 % in 6 sludges (lag times for approx 20 % of theoretical CH4 production: 4-6 weeks); insufficient data for 2 sludges. secondary sludge: degradation was 92% after 4 weeks with the first sludge and 90% after 5 weeks with the second (degradation related to theoretical methane and CO2 production) Test condition : 35 degrees C, due to storage of sludges before incubation, lag phase of methanogenesis could be increased in some sludges Reliability : (2) valid with restrictions Test procedure comparable to standard method and in accordance with generally accepted scientific standards; detailed documentation of test procedure and test conditions Flag : Critical study for SIDS endpoint 07.05.2004 (37) Type : anaerobic Inoculum : anaerobic sludge Concentration : 50 mg/l related to DOC (Dissolved Organic Carbon) related to Contact time : 56 day(s) Degradation : (±) % after Result : Deg. product : yes Method : Year : 1984 GLP : no Test substance : other TS: m-cresol, no purity reported Deg. products : 74-82-8 200-812-7 methane Method : primary and secondary anaerobic sewage sludge from 9 treatment plants diluted to 10 % in a mineral salts medium; degradation measured as gas pressure increase Remark : data have been published by the authors as a NTIS-study (previous data set) Result : in 2 different secondary sludges >75% degradation in 9 different primary sludges degradation 0-103% Test condition : incubation for 8 w at 35 degrees C Reliability : (2) valid with restrictions Test procedure comparable to standard method and in accordance with generally accepted scientific standards; sufficient documentation Flag : Critical study for SIDS endpoint 07.05.2004 (38) 82 UNEP PUBLICATIONS
OECD SIDS m-CRESOL 3. ENVIRONMENTAL FATE AND PATHWAYS ID: 108-39-4 DATE: 24.05.2004 Type : anaerobic Inoculum : anaerobic sludge Concentration : 50 mg/l related to DOC (Dissolved Organic Carbon) related to Deg. product : yes Method : Year : 1988 GLP : no Test substance : other TS: m-cresol, no purity reported (obtained from Aldrich Chemicals) Deg. products : 74-82-8 200-812-7 methane Method : primary anaerobic digesting sludge receiving a mixture of domestic and industrial wastewater Result : lag time 40 days, accompanied with inhibition of gas production net total gas production was 75 % +/- 15 % of the theoretical production (CH4+CO2) Test condition : - medium 2-3 g dw/l sludge - incubation for >= 60 d at 35 degrees C - 3 replicates - sterile controls for abiotic gas production - gas production measured with hand-held pressure meter Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail Flag : Critical study for SIDS endpoint 07.05.2004 (39) Type : aerobic Inoculum : activated sludge, domestic Concentration : .05 mg/l related to Test substance related to Contact time : Degradation : 35.6 (±) % after 5 day(s) Result : Deg. product : Method : other: Activated sludge test Year : 1985 GLP : no Test substance : other TS: 14C-labelled m-cresol presumably > 98 % purity; no specific activity given Remark : The bioaccumulation factor of the substance and its metabolites in activated sludge was 1100 Result : The readily biodegradable compounds methanol and phenol were about equally degraded like m-<strong>Cresol</strong> (41, 37 and 36 %) Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 24.05.2004 (26) Type : aerobic Inoculum : other bacteria: acclimatized mixed culture of pentachlorophenol-degrading bacteria Concentration : 5 mg/l related to Test substance related to Contact time : 29 day(s) Degradation : (±) % after UNEP PUBLICATIONS 83
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL MIXTURE I U
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OECD SIDS m- / p-CRESOL MIXTURE 1.
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