m-Cresol - ipcs inchem

OECD SIDS
m- / p-CRESOL MIXTURE
4. ECOTOXICITY ID: 15831-10-4
DATE: 24.05.2004
chemicals.
12.05.2004 (79)
Type : aquatic
Species : Photobacterium phosphoreum (Bacteria)
Exposure period : 15 minute(s)
Unit : mg/l
EC50 : 8
Analytical monitoring : no
Method : other: Microtox assay
Year : 1987
GLP : no
Test substance : other TS: m-cresol, analytical grade (either from Merck or EGA Chemie)
Remark : Not enough information supplied for assessment of the test
used (Test done according to Beckman manual). Although it is
suggested that Microtox may lack reproducibility due to
variations in bacterial cell suspensions [Bitton G (1983)
Bacterial and Biochemical Tests for Assessing Chemical
Toxicity in the Aquatic Environment: A Review. Crit Rev
Environ Control 13: 51 -67], no information is supplied on
the maintenance of the lyophilized bacteria, their age,
duration of reconstitution and other important parameters.
Reliability : (3) invalid
Unsuitable test system. Organisms are of marine origin.
Method is not appropriate for the hazard assessment of
chemicals.
12.05.2004 (80)
Type : aquatic
Species : other bacteria: Photobacterium (Vibrio) fischeri (marine)
Exposure period : 5 minute(s)
Unit : mg/l
EC50 : 8.2
Analytical monitoring : no
Method : other: Microtox assay
Year : 1981
GLP : no
Test substance : other TS: m-cresol, no purity reported
Remark : Although it is suggested that Microtox may lack
reproducibility due to variations in bacterial cell
suspensions [Bitton G (1983) Bacterial and Biochemical Tests
for Assessing Chemical Toxicity in the Aquatic Environment:
A Review. Crit Rev Environ Control 13: 51 -67], no
information is supplied on the maintenance of the
lyophilized bacteria, their age, duration of reconstitution
and other important parameters. In contrast to Bulich
[Bulich AA (1977), Aquatic Toxicology: Second conference
ASTM STP 667, American Society for Testing of Materials,
Philadelphia, pp 98 - 106], pH not buffered.
Test condition : 15 degrees C
Reliability : (3) invalid
Unsuitable test system. Organisms are of marine origin.
Method is not appropriate for the hazard assessment of
chemicals.
12.05.2004 (81)
Type : aquatic
Species : Escherichia coli (Bacteria)
Exposure period : 19 day(s)
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