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m-Cresol - ipcs inchem

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OECD SIDS<br />

p-CRESOL<br />

3. ENVIRONMENTAL FATE AND PATHWAYS ID: 106-44-5<br />

DATE: 24.05.2004<br />

Method : Seawater from California (USA) supplemented with 100, 500,<br />

and 1000 µg/l test substance. Analysis of subsamples with<br />

GC/MS<br />

Result : t1/2 = 295 h (100 µg/l)<br />

t1/2 = 215 h (500 µg/l)<br />

t1/2 = 325 h (1000 µg/l)<br />

Doubling time of population<br />

85 h (100 µg/l)<br />

40 h (500 µg/l)<br />

31 h (1000 µg/l)<br />

Test condition : Temp. 20+-2 degrees C<br />

Reliability : (2) valid with restrictions<br />

No standard test procedure, but in accordance with generally<br />

accepted scientific standards and described in sufficient<br />

detail<br />

24.05.2004 (50)<br />

Type : aerobic<br />

Inoculum : other: mixed microbial cultures<br />

Concentration : 1.6 mg/l related to Test substance<br />

3.2 mg/l related to Test substance<br />

Contact time : 8 day(s)<br />

Degradation : (±) % after<br />

Result :<br />

Deg. product :<br />

Method : other: APHA method (1980)<br />

Year : 1988<br />

GLP : no<br />

Test substance : other TS: p-cresol, no purity reported<br />

Method : BOD technique; determination of the degradation rate<br />

constant which is compared with those reported for natural<br />

waters<br />

Result : Pseudo-first-order rate constants (1/h):<br />

Degradation of p-cresol in BOD test solution 0.028<br />

Degradation of p-cresol in 5 natural waters 0.025 - 0.106 (mean 0.063)<br />

For comparison:<br />

Degradation of phenol in BOD test solution 0.020<br />

Degradation of phenol in 5 natural waters 0.046 - 0.110 (mean 0.075)<br />

p-<strong>Cresol</strong> is nearly as biodegradable as phenol.<br />

Test condition : 2.3 E8 cells/ml; 21 degrees C<br />

Reliability : (2) valid with restrictions<br />

No standard test procedure, but in accordance with generally accepted<br />

scientific standards and described in sufficient detail<br />

10.05.2004 (51)<br />

Type : aerobic<br />

Inoculum : other: mixed microbial cultures<br />

Concentration : 1.6 mg/l related to Test substance<br />

3.2 mg/l related to Test substance<br />

Deg. product :<br />

Method : other: BOD technique<br />

Year : 1989<br />

GLP : no<br />

Test substance : other TS: p-cresol, no purity reported<br />

Method : study targets to determine the effect of inoculum<br />

density on biodegradation rate; BOD technique<br />

Result : degradation rate was nearly independent on biomass<br />

concentration. First order rate constant 3.4 (+/- 0.24) x 10-1/day with 2.3<br />

UNEP PUBLICATIONS 209

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