28.01.2014 Views

m-Cresol - ipcs inchem

m-Cresol - ipcs inchem

m-Cresol - ipcs inchem

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

OECD SIDS<br />

m- / p-CRESOL MIXTURE<br />

5. TOXICITY ID: 15831-10-4<br />

DATE: 24.05.2004<br />

Remark : mean compound consumption (mg/kg bw/day):<br />

males females<br />

0 ppm 0 0<br />

625 ppm 96 116<br />

1250 ppm 194 239<br />

2500 ppm 402 472<br />

5000 ppm 776 923<br />

10000 ppm 1513 1693<br />

Result : All mice lived to the end of the study;<br />

as clinical signs of toxicity rough fur in females of the<br />

10000 ppm-group.<br />

10000 ppm: male, female reduced final body weight, slightly<br />

decreased feed consumption, males: reduced body weight gain<br />

At study termination significantly increased abs. and rel.<br />

liver weight were noted from males at 5000 ppm (abs:<br />

p

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!