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m-Cresol - ipcs inchem

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OECD SIDS<br />

m-CRESOL<br />

4. ECOTOXICITY ID: 108-39-4<br />

DATE: 24.05.2004<br />

Test substance : other TS: m-cresol, no purity reported<br />

Result : pertubation level 0.5 mg/l<br />

Reliability : (4) not assignable<br />

secondary literature<br />

12.05.2004 (71)<br />

4.5.1 CHRONIC TOXICITY TO FISH<br />

4.5.2 CHRONIC TOXICITY TO AQUATIC INVERTEBRATES<br />

4.6.1 TOXICITY TO SEDIMENT DWELLING ORGANISMS<br />

4.6.2 TOXICITY TO TERRESTRIAL PLANTS<br />

Species : other terrestrial plant: Lactuca sativa Ravel R2<br />

Endpoint : growth<br />

Exposure period : 14 day(s)<br />

Unit : mg/kg soil dw<br />

EC50 : 96<br />

Method : OECD Guide-line 208 "Terrestrial Plants, Growth Test"<br />

Year : 1993<br />

GLP : no data<br />

Test substance : other TS: m-cresol, purity >= 95 %<br />

Method : analytical monitoring at start and end of test<br />

Result : EC50 based on nominal concentration; for most of the<br />

examined phenols (including m-cresol) applied concentrations dropped but<br />

remained larger than 50 % of the nominal values.<br />

The 7-d EC50 was 69 mg/kg soil (original dimension µg/g soil).<br />

Reliability : (2) valid with restrictions<br />

Guideline study; applied test concentrations not stable<br />

during the test period<br />

Flag : Critical study for SIDS endpoint<br />

07.05.2004 (98)<br />

Species : Lactuca sativa (Dicotyledon)<br />

Endpoint : emergence<br />

Exposure period : 3 day(s)<br />

Unit : mg/l<br />

EC50 : 53<br />

Method : other: Seed germination test<br />

Year : 1978<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : As described by Reynolds 1975 (Characterization of osmotic restraints on<br />

lettuce fruit germination. Ann. Bot. 39, 791-796) and 1977 (Comparative<br />

effects of aliphatic com-pounds on inhibition of lettuce fruit germination.<br />

Ann. Bot. 41, 637-648)<br />

- Lettuce cultivar Great Lakes<br />

- Germination temperature 30 °C<br />

Result : Result was reported as "0.49 mmol/l" which equals 53 mg/l<br />

UNEP PUBLICATIONS 113

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