m-Cresol - ipcs inchem

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OECD SIDS m- / p-CRESOL MIXTURE 4. ECOTOXICITY ID: 15831-10-4 DATE: 24.05.2004 EC50 : 68 measured/nominal Analytical monitoring : no Method : other: Microtox assay Year : 1986 GLP : no data Test substance : other TS: m-cresol, no purity reported Remark : Inhibition of bioluminescence Modified microorganisms used which represent the metabolic potentials present in a wastewater treatment plant and some properties of a marine organism, but which are not identical to any known species in natural environments Test condition : - Wastewater bacteria (Eschericia coli) which were obtained from a wastewater treatment plant - Bacteria obtained the luciferase operon of Vibrio fischeri by transfer from luminescent E. coli - Incubation at 20 °C - Result calculated from the difference of the luminescence between controls and test substance taking into account the light emissions at 0 and 20 °C Reliability : (3) invalid Unsuitable test system. Organisms are of marine origin. Method is not appropriate for the hazard assessment of chemicals. 12.05.2004 (85) Type : aquatic Species : Escherichia coli (Bacteria) Exposure period : 2 hour(s) Unit : mg/l EC50 : 1000 Method : Year : 1954 GLP : Test substance : other TS: m-cresol, no purity reported Result : endpoint related to growth inhibition no effect on cell size Test condition : 37 degrees C Reliability : (3) invalid Methodological deficiencies 12.05.2004 (86) Type : aquatic Species : Escherichia coli (Bacteria) Exposure period : Unit : mg/l TT : 600 Analytical monitoring : no Method : Year : 1959 GLP : no Test substance : other TS: m-cresol, no purity reported Method : test organisms isolated from river water endpoint: inhibition of glucose metabolism Remark : TT = toxicity treshold; determined at 5 % effect compared to control Reliability : (3) invalid Methodological deficiencies 12.05.2004 (60) (87) 346 UNEP PUBLICATIONS
OECD SIDS m- / p-CRESOL MIXTURE 4. ECOTOXICITY ID: 15831-10-4 DATE: 24.05.2004 Type : aquatic Species : Pseudomonas fluorescens (Bacteria) Exposure period : Unit : mg/l TT : 40 Analytical monitoring : no Method : Year : 1960 GLP : no Test substance : other TS: m-cresol, no purity reported Remark : TT = toxicity treshold; determined at 5 % effect compared to control endpoint: inhibition of glucose metabolism Reliability : (3) invalid Methodological deficiencies 12.05.2004 (60) Type : aquatic Species : other bacteria: Pseudomonas Stamm Berlin 33/2 Exposure period : Unit : mg/l EC0 : 180 Analytical monitoring : no Method : other Year : 1982 GLP : no Test substance : other TS: m-cresol, no purity reported Remark : Effect endpoint: cell multiplication inhibition Reliability : (4) not assignable Insufficient documentation 12.05.2004 (47) Type : aquatic Species : Paramaecium caudatum (Protozoa) Exposure period : Unit : Method : Year : GLP : Test substance : other TS: m-cresol, no purity reported Result : pertubation level 0.9 mg/l Reliability : (4) not assignable secondary literature 12.05.2004 (61) Type : aquatic Species : other protozoa: Vorticella campanula Exposure period : Unit : Method : Year : GLP : Test substance : other TS: m-cresol, no purity reported Result : pertubation level 0.5 mg/l Reliability : (4) not assignable secondary literature UNEP PUBLICATIONS 347
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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OECD SIDS m-CRESOL 2. PHYSICO-CHEMI
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OECD SIDS m-CRESOL 3. ENVIRONMENTAL
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OECD SIDS m-CRESOL 6. REFERENCES ID
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OECD SIDS p-CRESOL 1. GENERAL INFOR
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