m-Cresol - ipcs inchem

OECD SIDS
m- / p-CRESOL MIXTURE
4. ECOTOXICITY ID: 15831-10-4
DATE: 24.05.2004
Test procedure comparable to standard method and in
accordance with generally accepted scientific standards;
sufficient documentation
Flag : Critical study for SIDS endpoint
12.05.2004 (43)
Type : static
Species : Oncorhynchus mykiss (Fish, fresh water)
Exposure period : 96 hour(s)
Unit : mg/l
LC50 : = 8.6
Limit test :
Analytical monitoring : no
Method :
Year : 1969
GLP : no
Test substance : other TS: m-cresol, reported to be "purified grade"
Method : 10 acclimated fish exposed per concentration, 20 served as
controls.
Result : LC50 (6 h) = 14.9 mg/l
LC50 (24 h) = 10.4 mg/l
LC50 (48 h) = 10.2 mg/l
In an additional test under flow-through conditions a
concentration of 10 mg/l caused total incapacitation in 15
of 20 fish within 11.5 min, after which a recovery to a
higher level of activity was observed
Test condition : 12 degree C, reconstituted water
Reliability : (2) valid with restrictions
Test procedure comparable to standard method and in
accordance with generally accepted scientific standards;
sufficient documentation
12.05.2004 (43)
Type : semistatic
Species : Poecilia reticulata (Fish, fresh water)
Exposure period : 96 hour(s)
Unit : mg/l
LC50 : 23.12
Limit test :
Analytical monitoring : no
Method :
Year : 1982
GLP : no
Test substance : other TS: m-cresol, purity 99 % (BDH Chemicals)
Method : 80 % of the test solution renewed at 12 h intervals
Test condition : 25-27 degrees Celsius, pH 7
Reliability : (2) valid with restrictions
Test procedure comparable to standard method and in
accordance with generally accepted scientific standards;
sufficient documentation
12.05.2004 (44)
Type : static
Species : Brachydanio rerio (Fish, fresh water)
Exposure period : 96 hour(s)
Unit : mg/l
LC0 : 11
LC50 : 15.9
LC100 : 22
328
UNEP PUBLICATIONS