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m-Cresol - ipcs inchem

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OECD SIDS<br />

p-CRESOL<br />

3. ENVIRONMENTAL FATE AND PATHWAYS ID: 106-44-5<br />

DATE: 24.05.2004<br />

measurement of 14CO2 radioactivity<br />

Reliability : (2) valid with restrictions<br />

No standard procedure but in accordance with generally accepted scientific<br />

standards and described in sufficient detail<br />

Flag : Critical study for SIDS endpoint<br />

24.05.2004 (42)<br />

Type : aerobic<br />

Inoculum : activated sludge, industrial<br />

Contact time :<br />

Degradation : = 100 (±) % after 10 day(s)<br />

Result : inherently biodegradable<br />

Deg. product :<br />

Method : OECD Guide-line 302 B "Inherent biodegradability: Modified Zahn-Wellens<br />

Test"<br />

Year : 1990<br />

GLP : no data<br />

Test substance : other TS: p-cresol, no purity reported<br />

Result : 90 % degradation during the log-phase (8 days)<br />

Test condition : Test substance conc. 50-400 mg/l DOC, 200-1000 mg/l COD<br />

acclimatization phase 2 days<br />

Reliability : (2) valid with restrictions<br />

Guideline study, basic data given<br />

Flag : Critical study for SIDS endpoint<br />

24.05.2004 (43)<br />

Type : aerobic<br />

Inoculum : activated sludge, adapted<br />

Concentration : 200 mg/l related to COD (Chemical Oxygen Demand)<br />

related to<br />

Contact time :<br />

Degradation : = 96 (±) % after 5 day(s)<br />

Result : inherently biodegradable<br />

Deg. product :<br />

Method : other: batch system (similar to OECD 302B "Zahn-Wellens-Test")<br />

Year : 1976<br />

GLP : no data<br />

Test substance : other TS: p-cresol, no purity reported<br />

Method : - Test compound was sole source of carbon<br />

- Inoculum density: 100 mg dry matter/l; gradual increase of TS<br />

concentration during 20 days adaptation period<br />

- COD measured<br />

- With volatile substances a test without inocculum was done to<br />

differentiate the actual biological degradation from the losses due to mere<br />

volatilization<br />

Result : Initial degradation rate: 55.0 mg COD/g/h<br />

Test condition : 20 +/-3 degree C; pH 7.2; mineral salts medium; dark;<br />

continuously stirred<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

basic data given<br />

Flag : Critical study for SIDS endpoint<br />

24.05.2004 (44)<br />

Type : anaerobic<br />

Inoculum : anaerobic sludge<br />

Deg. product : yes<br />

Method :<br />

206<br />

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