m-Cresol - ipcs inchem

OECD SIDS
m-CRESOL
3. ENVIRONMENTAL FATE AND PATHWAYS ID: 108-39-4
DATE: 24.05.2004
the environment.
Reliability : (2) valid with restrictions
Expert judgement
Flag : Critical study for SIDS endpoint
08.01.2003
3.1.3 STABILITY IN SOIL
Type : laboratory
Radiolabel :
Concentration :
Soil temperature : °C
Soil humidity :
Soil classification :
Year :
Deg. product :
Method :
Year : 1990
GLP : no
Test substance : other TS: m-cresol, no purity reported
Method : Bench-scale experiments with contaminated soil.
Determination of passive evaporation and biodegradation of
cresols
Result : passive evaporation half-life 4.2 - 4.8 weeks
biodegradation: after 4 days below detection limit
Test condition : Passive evaporation: plastic petri plates (88x18 mm) placed
on canopy-covered table. Temp. 10-17 degrees C, humidity 75%
Shake-flask biodegradation test: 8-25 g soil mixed with 50
ml buffer solution; shaken for 4 days
Reliability : (3) invalid
Methodological deficiencies
07.05.2004 (27)
Type : laboratory
Radiolabel : yes
Concentration :
Soil temperature : °C
Soil humidity :
Soil classification :
Year :
Deg. product :
Method : other: see Method below
Year : 1985
GLP : no
Test substance : as prescribed by 1.1 - 1.4
Method : Inocolum: subsurface microbial community of a pristine aquifer (Lula,
Okla.)
Soil: aquifer solid sample, unconsilated sand, from a depth of 4.5-5.6 m
below surface
All substances were radiolabeled.
Incubation period: 8 months
Determination of mineralization via 14CO2 evolution
Remark : The highest percent biodegradation achieved for nearly all the substances
tested was 35% (e.g. anilin, which is the standard reference substance for
all ready tests in OECD 301 achieved after 100 days only 15%
biodegradation).
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