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m-Cresol - ipcs inchem

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OECD SIDS<br />

m- / p-CRESOL MIXTURE<br />

4. ECOTOXICITY ID: 15831-10-4<br />

DATE: 24.05.2004<br />

Remark : Effect endpoint: immobilisation<br />

Test condition : Reconstituted hard water 200 mg/l CaCO3<br />

pH 7.8-8.2<br />

dissolved oxigen >25% of saturation<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

sufficient documentation<br />

12.05.2004 (57) (58)<br />

Type : other: not specified<br />

Species : Daphnia magna (Crustacea)<br />

Exposure period : 48 hour(s)<br />

Unit : mg/l<br />

LC50 : 18.8<br />

Limit Test : no<br />

Analytical monitoring : no data<br />

Method : other: according to the method described by Parkhurst et al. 1977<br />

Year : 1979<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : Parkhurst BR, Gehrs CW, Rubin IB (1977): Proceedings of ASTM<br />

2nd Annual Symposium on Aquatic Toxicology, 122-130<br />

Test condition : Daphnia magna used in the test were adults.<br />

100-ml test beakers were filled with 80 ml test solution and<br />

4 daphnia. All the tests were run in triplicate.<br />

Temperature during the test: 25 +/- 0.5°C<br />

12h light/dark cycle<br />

Test solution was prepared with filtered spring water (pH<br />

7.8 alkalinity mg/l, hardness 140 mg/l)<br />

Control beakers were used<br />

48h-EC50 values were obtained by PROBIT<br />

Test substance : The test substance was obtained from an effluent<br />

Reliability : (2) valid with restrictions<br />

Study well documented (method description in an other<br />

reference) with some restriccions. Age of daphnia used in<br />

the test is not clear. Daphnias were "adults" and adults can<br />

be older than 24h (24h is suggested in the guideline);<br />

temperature was 25°C (in guideline is suggested: 18-22°C);<br />

12 daphnia were used for each test concentration (in<br />

guideline are suggested: 40)<br />

12.05.2004 (59)<br />

Type : static<br />

Species : Daphnia sp. (Crustacea)<br />

Exposure period : 48 hour(s)<br />

Unit : mg/l<br />

TT : 28<br />

Analytical monitoring : no<br />

Method :<br />

Year : 1959<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : test organisms were reared from daphnids collected in<br />

surface water<br />

Remark : TT = Toxicity threshold; test organisms were reared from<br />

daphnids collected in surface water<br />

Test condition : river water, pH 7.5<br />

Reliability : (3) invalid<br />

334<br />

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