m-Cresol - ipcs inchem

OECD SIDS
p-CRESOL
4. ECOTOXICITY ID: 106-44-5
DATE: 24.05.2004
Method :
Year : 1984
GLP : no
Test substance : other TS: p-cresol, no purity reported
Method : Determination of sublethal endpoints with fish larvae
Result : concentrations up to 4.2 mg/l had no significant effect on
larval survival or growth
larval RNA, DNA and protein content, although reduced at
2.57 mg/l, was not significantly affected at any
concentration
Test condition : Larval fish within 24 h of hatching, 25-35 per chamber
medium: soft Lake Superior water
5 TS concentrations, range 0.4-4.2 mg/l
Reliability : (2) valid with restrictions
Test procedure comparable to standard method and in
accordance with generally accepted scientific standards;
water chemistry data not reported
07.05.2004 (82)
Type : semistatic
Species : other: Lepidocephalichthys guntea (freshwater fish)
Exposure period : 96 hour(s)
Unit : mg/l
Limit test :
Analytical monitoring : no
Method : other: see test conditions
Year : 1998
GLP : no
Test substance : other TS: p-cresol, analytical grade
Result : LC50 (24 h) = 21.0 (16.42 - 26.86) mg/l
LC50 (48 h) = 18.0 (14.70 - 22.03) mg/l
LC50 (72 h) = 16.0 (13.20 - 19.39) mg/l
LC50 (96 h) = 14.0 (11.82 - 16.58) mg/l
Test condition : fish lenght 5.16 +- 0.38 cm, weight 1.46 +- 0.27 g
27-29 degrees C; pH 7.0-7.3; oxigen 7.0-7.2 mg/l; hardness
80-86 mg/l CaCO3
10 fish/concentration
medium renewed daily
Reliability : (2) valid with restrictions
Study in accordance with generally accepted scientific
standards and described in sufficient detail
07.05.2004 (83)
Type : static
Species : Gadus morrhua (Fish, fresh water)
Exposure period : 96 hour(s)
Unit : mg/l
EC50 : = 5
Limit test :
Analytical monitoring : yes
Method :
Year : 1985
GLP : no
Test substance : other TS: p-cresol, purity > 98 % as determined by GC (obtained from
Merck)
Method : Effect endpoints: death, pathology, inhibition of cleavage
and differentiation, pigment defects
Result : parallel test with larvae (6 days after hatching) showed
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