m-Cresol - ipcs inchem

OECD SIDS
p-CRESOL
3. ENVIRONMENTAL FATE AND PATHWAYS ID: 106-44-5
DATE: 24.05.2004
Method : Initial sludge concentration 30 mg dw/l
reference compound aniline
Remark : Incubation period 20-40 days; no oxygen uptake curve given;
degradation of reference substance aniline >=60 % within 28 days
Result : The oxygen uptake curves are not reported. However, the authors state
that all test compounds revealed the lag phase, biodegradation phase and
the plateau region within a period of 10 days, indicating that the 10-day
window criteria is met.
first order biodegradation constant (hr-1): ln k = -5.87
maximum specific substrate uptake rate per unit biomass km = 18.5 / day
(Aniline 16.1, Phenol 16.9)
p-Cresol is slightly better biodegradable than phenol and aniline
Test condition : Inoculum /test organism
- Type of sludge: activated
- Source: municipal treatment plant, receiving predominantly domestic
sewage
- Initial cell concentration: 30 mg/l
Test system
- Culturing apparatus: Sapromat
- Closed vessels used: yes
Initial test substance concentration: 100 mg/l
Duration of the test: 20-40 days
Test conditions
- Composition of synthetic medium: OECD
- Test temperature: 25 degrees C
Reference substance: aniline 100 mg/l
Reliability : (2) valid with restrictions
Study comparable to OECD Guideline 301C
Flag : Critical study for SIDS endpoint
11.05.2004 (41)
Type : aerobic
Inoculum : other: natural microorganism communities from water and sediment
Concentration : 200 µg/l related to Test substance
related to
Contact time :
Degradation : 50 - 100 (±) % after 43 hour(s)
Result :
Deg. product :
Method :
Year : 1983
GLP : no
Test substance : other TS: p-cresol, no purity reported [ring-U-14C] p-cresol
Method : Biodegradation in natural aquatic test systems:
1.shake-flasks with water, 2.shake flasks with water and
sediment, 3.intact sediment-water cores (eco-cores)
3 sample sites in a river estuary
Result : First order half-lives:
water flasks: 9.5-43 h
sediment flasks: 5.9-11 h
eco-core: 3.0-16 h
Test condition : 1. shake flask tests with filtered water
2. shake flask tests with filtered water and 500 mg/l
organic sediment (30-50% OC). Sediment collected from the
top 5 cm of the sediment surface
3. Eco-core samples had an aerobic layer of detritus
overlying anaerobic sediment.
All flasks incubated with radiolabelled TS and maintained at
18 degrees C in the dark
Analysis: water samples filtered and analysed by HPLC,
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