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m-Cresol - ipcs inchem

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OECD SIDS<br />

m-CRESOL<br />

5. TOXICITY ID: 108-39-4<br />

DATE: 24.05.2004<br />

24.09.2002 (139)<br />

Type : Ames test<br />

System of testing : Salmonella typhimurium TA 100, TA 1530, TA 1535, TA 1538,TA 1950, TA<br />

1951, TA 1952, G 46<br />

Test concentration : 0.5 % in ethanol<br />

Cycotoxic concentr. :<br />

Metabolic activation : no data<br />

Result : ambiguous<br />

Method : other: according to Ames Mutat. Res. 31,347 (1975); Science 176, 47<br />

(1972)<br />

Year : 1975<br />

GLP : no data<br />

Test substance : other TS: no data on purity<br />

Remark : a questionable effect was produced in<br />

the strain TA 1535<br />

Reliability : (4) not assignable<br />

documentation insufficient for assessment<br />

20.09.2002 (140)<br />

Type : other: SOS-Chromotest<br />

System of testing : Escherichia coli PQ37<br />

Test concentration : no data<br />

Cycotoxic concentr. :<br />

Metabolic activation : without<br />

Result : positive<br />

Method : other: After termination of the nitrosation of m-cresol with ammonium<br />

sulphamate, test was performed according to Quillardet, Mutat. Res.<br />

147,65 (1985)<br />

Year : 1989<br />

GLP : no data<br />

Test substance : other TS: no data<br />

Reliability : (4) not assignable<br />

documentation insufficient for assessment<br />

24.09.2002 (141)<br />

Type : other: Prophage induction assay<br />

System of testing : Escherichia coli / Bacteriophage lambda<br />

Test concentration :<br />

Cycotoxic concentr. :<br />

Metabolic activation :<br />

Result : positive<br />

Method :<br />

Year :<br />

GLP :<br />

Test substance :<br />

Reliability : (4) not assignable<br />

abstract only<br />

20.09.2002 (142)<br />

Type : Cytogenetic assay<br />

System of testing : Allium cepa<br />

Test concentration :<br />

Cycotoxic concentr. :<br />

Metabolic activation : without<br />

Result : negative<br />

Method :<br />

Year : 1948<br />

UNEP PUBLICATIONS 143

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