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m-Cresol - ipcs inchem

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OECD SIDS<br />

m-CRESOL<br />

4. ECOTOXICITY ID: 108-39-4<br />

DATE: 24.05.2004<br />

GLP : no data<br />

Test substance : other TS: m-cresol, purity > 95 %<br />

Remark : Effect endpoint: immobilisation<br />

Result : Result is reported as 24h IC50 "0.178 mmol/l" (which equals 19.2 mg/l)<br />

Test condition : Reconstituted hard water 200 mg/l CaCO3<br />

pH 7.8-8.2<br />

dissolved oxigen >25% of saturation<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

sufficient documentation<br />

07.05.2004 (67) (68)<br />

Type : other: not specified<br />

Species : Daphnia magna (Crustacea)<br />

Exposure period : 48 hour(s)<br />

Unit : mg/l<br />

LC50 : 18.8<br />

Limit Test : no<br />

Analytical monitoring : no data<br />

Method : other: according to the method described by Parkhurst et al. 1977<br />

Year : 1979<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : Parkhurst BR, Gehrs CW, Rubin IB (1977): Proceedings of ASTM 2nd<br />

Annual Symposium on Aquatic Toxicology, 122-130<br />

Test condition : Daphnia magna used in the test were adults.<br />

100-ml test beakers were filled with 80 ml test solution and 4 daphnia. All<br />

the tests were run in triplicate.<br />

Temperature during the test: 25 +/- 0.5°C<br />

12h light/dark cycle<br />

Test solution was prepared with filtered spring water (pH 7.8 alkalinity mg/l,<br />

hardness 140 mg/l)<br />

Control beakers were used<br />

48h-EC50 values were obtained by PROBIT<br />

Test substance : The test substance was obtained from an effluent<br />

Reliability : (3) invalid<br />

Methodological deficiencies (method description is in the other reference<br />

from the same author). Age of daphnias used in the test is not clearly<br />

specified: test daphnias were "adults" (in the OECD guideline a 24h-old<br />

daphnia is suggested); temperature during the test was 25°C (in the<br />

guideline is suggested: 18-22°C); 12 daphnia were used for each test<br />

concentration (in the guideline 40 daphnias are suggested)<br />

07.05.2004 (69)<br />

Type : static<br />

Species : Daphnia sp. (Crustacea)<br />

Exposure period : 48 hour(s)<br />

Unit : mg/l<br />

TT : 28<br />

Analytical monitoring : no<br />

Method :<br />

Year : 1959<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : test organisms were reared from daphnids collected in<br />

surface water<br />

UNEP PUBLICATIONS 99

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