m-Cresol - ipcs inchem

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OECD SIDS p-CRESOL 4. ECOTOXICITY ID: 106-44-5 DATE: 24.05.2004 Endpoint : other: Photosynthesis and Respiration Exposure period : Unit : Limit test : Analytical monitoring : no Method : Year : 1983 GLP : no Test substance : other TS: p-cresol, purity at least 99 % Method : Algae exposed in a open channel experimental stream set. Result : The net oxygen production decreased from 0.084 (control) to 0.022 mg O2/mg DW with 8 mg/l TS. Respiration in the dark increased from -0.064 (control) to -0.182 O2/mg DW. Reliability : (3) invalid Unsuitable test system 07.05.2004 (104) 4.4 TOXICITY TO MICROORGANISMS E.G. BACTERIA 238 Type : aquatic Species : activated sludge of a predominantly domestic sewage Exposure period : 2 hour(s) Unit : mg/l IC50 : = 439.5 calculated Analytical monitoring : no Method : other: similar to OECD Guideline 209 Year : 1999 GLP : no Test substance : other TS: p-cresol, analytical grade Method : O2 measured with an optical scanning respirometer; endpoint: inhibition of respiration rate Test condition : pH 7.0; temp. 20 degrees C Reliability : (2) valid with restrictions Study in accordance with generally accepted scientific standards and described in sufficient detail Flag : Critical study for SIDS endpoint 07.05.2004 (105) Type : aquatic Species : activated sludge of a predominantly domestic sewage Exposure period : Unit : mg/l EC75 : = 16.5 Analytical monitoring : no Method : other: inhibition of nitrification process Year : 1966 GLP : no Test substance : other TS: p-cresol, no purity reported Method : Quantitative determination of the nitrification rate (1st step, NH4 to NO2) colorimetric measurement of the NO2/NO3 concentration; static test system pre-cleaned activated sludge in particle-free communal waste water (BOD5: 250 mg/l; NH4-N/l: 50-80 mg) Remark : effect: inhibition of ammonia oxidation Test condition : Exposure period: 2-4h; 25 degree C; pH 7.6-7.8 Reliability : (2) valid with restrictions UNEP PUBLICATIONS
OECD SIDS p-CRESOL 4. ECOTOXICITY ID: 106-44-5 DATE: 24.05.2004 Study in accordance with generally accepted scientific standards and described in sufficient detail Flag : Critical study for SIDS endpoint 07.05.2004 (106) Type : Aquatic Species : Nitrosomonas sp. (Bacteria) Exposure period : 24 hour(s) Unit : mg/l IC50 : = 27 Analytical monitoring : No Method : other: Inhibition of nitrification, comparable to ISO/DIS 9509 Year : 1991 GLP : No Test substance : other TS: p-cresol, no purity reported Method : culture obtained from mixed liquor of a treatment plant Remark : Effect: inhibition of N-oxidation Test condition : 25 degrees C Reliability : (2) valid with restrictions Study in accordance with generally accepted scientific standards and described in sufficient detail 07.05.2004 (107) Type : Aquatic Species : Tetrahymena pyriformis (Protozoa) Exposure period : 48 hour(s) Unit : mg/l EC50 : = 157 Analytical monitoring : No Method : other: growth inhibition test Year : 1996 GLP : No Test substance : other TS: p-cresol, purity at least 95 % Test condition : 27 +- 1 degrees C; pH 7.35 Reliability : (2) valid with restrictions Study in accordance with generally accepted scientific standards and described in sufficient detail 07.05.2004 (108) Type : Aquatic Species : Tetrahymena pyriformis (Protozoa) Exposure period : 24 hour(s) Unit : mg/l LC100 : = 400 Analytical monitoring : No Method : Year : 1978 GLP : No Test substance : other TS: p-cresol, no purity reported Test condition : 28 degrees C Reliability : (2) valid with restrictions Study in accordance with generally accepted scientific standards and described in sufficient detail 07.05.2004 (109) Type : Aquatic Species : Tetrahymena pyriformis (Protozoa) Exposure period : 24 hour(s) UNEP PUBLICATIONS 239
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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OECD SIDS m-CRESOL 2. PHYSICO-CHEMI
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OECD SIDS m-CRESOL 3. ENVIRONMENTAL
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OECD SIDS m-CRESOL 4. ECOTOXICITY I
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OECD SIDS m- / p-CRESOL MIXTURE I U
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OECD SIDS m- / p-CRESOL MIXTURE 1.
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