m-Cresol - ipcs inchem

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OECD SIDS m- / p-CRESOL MIXTURE 4. ECOTOXICITY ID: 15831-10-4 DATE: 24.05.2004 Year : 1985 GLP : no Test substance : other TS: m-cresol, purity 99.5 % Method : 6 different pure bacteria cultures: 3 isolated from a laboratory activated sludge, 2 from activated sludge from a municipal plant receiving some industry wastewater, and 1 from a lake sediment Effect: 50 % resazurin reduction (determination of dehydrogenase activity) Result : from laboratory sludges: EC50 = >500, 225, and 410 mg/l from activated sludges: EC50 = 360 and >500 mg/l from lake sediment: EC50 = >500 mg/l Test condition : 21 degrees C; incubation 30-60 min Test substance : purity 99.5% Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 12.05.2004 (71) Type : aquatic Species : other bacteria: Aerobic heterotrophic Exposure period : 49 hour(s) Unit : mg/l IC 50 : 440 Analytical monitoring : no Method : Year : 1991 GLP : no Test substance : other TS: m-cresol, no purity reported Method : culture obtained from mixed liquor of a treatment plant Remark : Effect: inhibition of respiration; prolonged incubation compared with ISO 8192 Test condition : 25 and 35 degrees C Reliability : (2) valid with restrictions Test procedure comparable to standard method and in accordance with generally accepted scientific standards; sufficient documentation 12.05.2004 (72) Type : aquatic Species : other bacteria: Methanogenic bacteria Exposure period : 96 hour(s) Unit : mg/l IC 50 : 890 Analytical monitoring : no Method : other: Owen, W.F.: Bioassay for Monitoring Biochemical Methane Potential and Anaerobic Toxicity. Water Res. 13, 485 (1979) Year : 1991 GLP : no Test substance : other TS: m-cresol, no purity reported Remark : Effect: inhibition of gas production Test condition : 35 degrees C Reliability : (2) valid with restrictions Test procedure comparable to standard method and in accordance with generally accepted scientific standards; sufficient documentation 12.05.2004 (72) 340 UNEP PUBLICATIONS
OECD SIDS m- / p-CRESOL MIXTURE 4. ECOTOXICITY ID: 15831-10-4 DATE: 24.05.2004 Type : aquatic Species : Nitrosomonas sp. (Bacteria) Exposure period : 24 hour(s) Unit : mg/l IC 50 : .78 Analytical monitoring : no Method : other: Inhibition of nitrification, comparable to ISO/DIS 9509 Year : 1991 GLP : no Test substance : other TS: m-cresol, no purity reported Method : culture obtained from mixed liquor of a treatment plant Remark : Effect: inhibition of N-oxidation Test condition : 25 degrees C Reliability : (3) invalid In principal the test is comparable to standard methods, but the authors state that the compounds with log IC50
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 14: T
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Nobel W, Ma
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL Available P
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m-CRESOL 1. GENERAL INFOR
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OECD SIDS m-CRESOL 2. PHYSICO-CHEMI
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OECD SIDS m-CRESOL 3. ENVIRONMENTAL
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OECD SIDS m-CRESOL 4. ECOTOXICITY I
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OECD SIDS p-CRESOL 1. GENERAL INFOR
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OECD SIDS p-CRESOL 6. REFERENCES ID
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