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m-Cresol - ipcs inchem

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OECD SIDS<br />

m-CRESOL<br />

3. ENVIRONMENTAL FATE AND PATHWAYS ID: 108-39-4<br />

DATE: 24.05.2004<br />

Initial test substance concentration: 100 mg/l<br />

Duration of the test: 20-40 days<br />

Test conditions<br />

- Composition of synthetic medium: OECD<br />

- Test temperature: 25 degrees C<br />

Reference substance: aniline 100 mg/l<br />

Reliability : (2) valid with restrictions<br />

study comparable to OECD Guideline 301 C<br />

Flag : Critical study for SIDS endpoint<br />

11.05.2004 (34)<br />

Type : aerobic<br />

Inoculum : activated sludge, industrial<br />

Contact time :<br />

Degradation : 96 (±) % after 10 day(s)<br />

Result :<br />

Deg. product :<br />

Method : OECD Guide-line 302 B "Inherent biodegradability: Modified Zahn-Wellens<br />

Test"<br />

Year : 1990<br />

GLP : no data<br />

Test substance : other TS: m-cresol, no purity reported<br />

Result : 90% degradation during the log-phase (8 days)<br />

Test condition : Test substance conc. 50-400 mg/l DOC, 200-1000 mg/l COD<br />

acclimatization phase 2 days<br />

Reliability : (2) valid with restrictions<br />

Guideline study; basic data given<br />

Flag : Critical study for SIDS endpoint<br />

24.05.2004 (35)<br />

Type : aerobic<br />

Inoculum : activated sludge, adapted<br />

Concentration : 200 mg/l related to COD (Chemical Oxygen Demand)<br />

related to<br />

Contact time :<br />

Degradation : 95.5 (±) % after 5 day(s)<br />

Result :<br />

Deg. product :<br />

Method : other: batch system (similar to OECD 302B "Zahn-Wellens Test")<br />

Year : 1976<br />

GLP : no<br />

Test substance : other TS: m-cresol, no purity reported<br />

Method : - Test compound was sole source of carbon<br />

- Inoculum density: 100 mg dry matter/l; gradual increase of TS<br />

concentration during 20 days adaptation period<br />

- With volatile substances a test without inocculum was done to<br />

differentiate the actual biological degradation from the losses due to mere<br />

volatilization<br />

Result : Initial degradation rate: 55.0 mg COD/g/h<br />

Test condition : 20 +- 3 degrees C; pH 7.2; mineral salts medium; dark; continuously stirred<br />

Reliability : (2) valid with restrictions<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

basic data given<br />

Flag : Critical study for SIDS endpoint<br />

24.05.2004 (36)<br />

Type : anaerobic<br />

UNEP PUBLICATIONS 81

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