m-Cresol - ipcs inchem

OECD SIDS
m- / p-CRESOL MIXTURE
3. ENVIRONMENTAL FATE AND PATHWAYS ID: 15831-10-4
DATE: 24.05.2004
Test was performed in two paralleles.
Reliability : (2) valid with restrictions
Guideline Study
12.05.2004 (22)
Type : aerobic
Inoculum : activated sludge, domestic
Concentration : 100 mg/l related to Test substance
related to
Contact time :
Degradation : 80 - 95 (±) % after 40 day(s)
Result :
Deg. product :
Method : other: comparable to OECD Guide-line 301 C
Year : 1981
GLP : no
Test substance : other TS: m-cresol, purity > 99 %
Method : Initial sludge concentration: 30 mg d.w./l; aniline as
reference compound
Remark : Incubation period: 20-40 days; no oxygen uptake curve given;
degradation of reference substance aniline >/= 60 % within
28 days
Result : The oxygen uptake curves are not reported. However, the authors state
that all test compounds revealed the lag phase, biodegradation phase and
the plateau region within a period of 10 days, indicating that the 10-day
window criteria is met.
First order biodegradation constant (hr-1): ln k = -5.77
maximum specific substrate uptake rate per unit biomass km = 17.3 / day
(Aniline 16.1, Phenol 16.9).
m-Cresol is slightly better biodegradable than phenol and aniline.
Test condition : Inoculum /test organism
- Type of sludge: activated
- Source: municipal treatment plant, receiving predominantly
domestic sewage
- Initial cell concentration: 30 mg/l
Test system
- Culturing apparatus: Sapromat
- Closed vessels used: yes
Initial test substance concentration: 100 mg/l
Duration of the test: 20-40 days
Test conditions
- Composition of synthetic medium: OECD
- Test temperature: 25 degrees C
Reference substance: aniline 100 mg/l
Reliability : (2) valid with restrictions
study comparable to OECD Guideline 301 C
Flag : Critical study for SIDS endpoint
12.05.2004 (23)
Type : aerobic
Inoculum : activated sludge, industrial
Contact time :
Degradation : 96 (±) % after 10 day(s)
Result :
Deg. product :
Method : OECD Guide-line 302 B "Inherent biodegradability: Modified Zahn-Wellens
Test"
Year : 1990
GLP : no data
Test substance : other TS: m-cresol, no purity reported
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