m-Cresol - ipcs inchem

OECD SIDS
m- / p-CRESOL MIXTURE
4. ECOTOXICITY ID: 15831-10-4
DATE: 24.05.2004
1 0 0 - -
0.1 100 100 86.5 77.1
Reliability : (3) invalid
Methodological deficiencies
12.05.2004 (89)
4.6.3 TOXICITY TO SOIL DWELLING ORGANISMS
4.6.4 TOX. TO OTHER NON MAMM. TERR. SPECIES
Species : other avian: Agelaius phoeniceus (red-winged blackbird)
Endpoint : mortality
Exposure period :
Unit : mg/kg bw
LD50 oral : 113
Method :
Year : 1983
GLP : no data
Test substance : other TS: m-cresol
Test condition : birds pre-conditioned to captivity for 2 to 6 weeks
dosed by gavage with solution in propylene glycol or by
pellets resp. gelatin capsules
Reliability : (2) valid with restrictions
Unsuitable test system
11.02.2003 (90)
4.7 BIOLOGICAL EFFECTS MONITORING
4.8 BIOTRANSFORMATION AND KINETICS
Remark : In aquarium water of 12 species of freshwater fish 48 h
after exposure to 3-15 mg/l m-cresol, cresyl sulphate
(55-64% of 14C recovered) or m-hydroxybenzoic acid (0-39 %)
were found
In bile of 11 species, cresyl glucuronide (63-74 %), cresyl
sulphate (8-20 %) and m-hydrobenzoic acid (5-12 %) were
found
Unchanged m-cresol detected in both aquarium water and bile
Test substance : m-[U-14C]cresol
Reliability : (2) valid with restrictions
No standard test procedure, but in accordance with generally
accepted scientific standards and described in sufficient
detail
17.10.2001 (91)
4.9 ADDITIONAL REMARKS
350
Memo : Sea urchin test
Remark : Strongylocentrotus droebachiensis (sea urchin):
static test, 5 degrees C
Determined effect endpoints: death, pathology, inhibition of
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