m-Cresol - ipcs inchem

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OECD SIDS m-CRESOL 4. ECOTOXICITY ID: 108-39-4 DATE: 24.05.2004 Test substance : other TS: m-cresol, no purity reported Remark : TT = Toxicity threshold; determined at 5 % effect compared to control Test condition : 25 degrees C; initial pH 6.9 Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 07.05.2004 (86) Type : aquatic Species : Tetrahymena pyriformis (Protozoa) Exposure period : 24 hour(s) Unit : mg/l LC100 : 375 Analytical monitoring : no Method : other: Microtox Year : 1978 GLP : no Test substance : other TS: m-cresol, no purity reported Test condition : 28 degrees C Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 12.05.2004 (87) Type : aquatic Species : Uronema parduzci (Protozoa) Exposure period : 20 hour(s) Unit : mg/l TT : 62 Analytical monitoring : no Method : other: cell multiplication inhibition test Year : 1980 GLP : no Test substance : other TS: m-cresol, no purity reported Remark : TT = Toxicity threshold; determined at 5 % effect compared to control Test condition : 25 degrees C; initial pH 6.9 Reliability : (2) valid with restrictions No standard test procedure, but in accordance with generally accepted scientific standards and described in sufficient detail 07.05.2004 (88) Type : aquatic Species : Photobacterium phosphoreum (Bacteria) Exposure period : 5 minute(s) Unit : mg/l EC50 : 11 Analytical monitoring : no Method : other: Microtox assay Year : 1983 GLP : no data Test substance : other TS: m-cresol, no purity reported 108 UNEP PUBLICATIONS
OECD SIDS m-CRESOL 4. ECOTOXICITY ID: 108-39-4 DATE: 24.05.2004 Remark : effect: reduction of bioluminescence Secondary literature. Not enough information supplied for assessment. Although the author suggests that Microtox may lack reproductibility due to variations in bacterial cell suspensions, no information is supplied on the maintenance of the lyophilized bacteria, their age, duration of reconstitution and other important parameters. Reliability : (3) invalid Unsuitable test system. Organisms are of marine origin. Method is not appropriate for the hazard assessment of chemicals. 07.05.2004 (89) Type : aquatic Species : Photobacterium phosphoreum (Bacteria) Exposure period : 15 minute(s) Unit : mg/l EC50 : 8 Analytical monitoring : no Method : other: Microtox assay Year : 1987 GLP : no Test substance : other TS: m-cresol, analytical grade (either from Merck or EGA Chemie) Remark : Not enough information supplied for assessment of the test used (Test done according to Beckman manual). Although it is suggested that Microtox may lack reproducibility due to variations in bacterial cell suspensions [Bitton G (1983) Bacterial and Biochemical Tests for Assessing Chemical Toxicity in the Aquatic Environment: A Review. Crit Rev Environ Control 13: 51 -67], no information is supplied on the maintenance of the lyophilized bacteria, their age, duration of reconstitution and other important parameters. Reliability : (3) invalid Unsuitable test system. Organisms are of marine origin. Method is not appropriate for the hazard assessment of chemicals. 07.05.2004 (90) Type : aquatic Species : other bacteria: Photobacterium (Vibrio) fischeri (marine) Exposure period : 5 minute(s) Unit : mg/l EC50 : 8.2 Analytical monitoring : no Method : other: Microtox assay Year : 1981 GLP : no Test substance : other TS: m-cresol, no purity reported Remark : Although it is suggested that Microtox may lack reproducibility due to variations in bacterial cell suspensions [Bitton G (1983) Bacterial and Biochemical Tests for Assessing Chemical Toxicity in the Aquatic Environment: A Review. Crit Rev Environ Control 13: 51 -67], no information is supplied on the maintenance of the lyophilized bacteria, their age, duration of reconstitution and other important parameters. In contrast to Bulich [Bulich AA (1977), Aquatic Toxicology: Second conference ASTM STP 667, American Society for Testing of Materials, Philadelphia, pp 98 - 106], pH not buffered. Test condition : 15 degrees C Reliability : (3) invalid Unsuitable test system. Organisms are of marine origin. Method is not appropriate for the hazard assessment of chemicals. 07.05.2004 (91) UNEP PUBLICATIONS 109
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OECD SIDS m- / p-CRESOL FOREOWRD IN
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OECD SIDS m- / p-CRESOL 11. Comment
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OECD SIDS m- / p-CRESOL of mice. In
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OECD SIDS m- / p-CRESOL SIDS Initia
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OECD SIDS m- / p-CRESOL Table 3: Es
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OECD SIDS m- / p-CRESOL m-cresol an
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OECD SIDS m- / p-CRESOL extensive s
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OECD SIDS m- / p-CRESOL et al. 1993
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OECD SIDS m- / p-CRESOL study in wh
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OECD SIDS m- / p-CRESOL Conclusion:
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OECD SIDS m- / p-CRESOL Table 5: m-
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OECD SIDS m- / p-CRESOL ≥300 ppm,
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OECD SIDS m- / p-CRESOL Atrophy and
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OECD SIDS m- / p-CRESOL p-Cresol p-
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OECD SIDS m- / p-CRESOL 3.1.7 Carci
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OECD SIDS m- / p-CRESOL weights wer
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OECD SIDS m- / p-CRESOL drowsiness,
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OECD SIDS m- / p-CRESOL and reduced
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OECD SIDS m- / p-CRESOL The most se
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OECD SIDS m- / p-CRESOL Table 15: T
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OECD SIDS m- / p-CRESOL 5 RECOMMEND
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OECD SIDS m- / p-CRESOL BRRC (Bushy
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OECD SIDS m- / p-CRESOL Hamster Ova
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OECD SIDS m- / p-CRESOL Vernot EH,
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OECD SIDS m- / p-CRESOL √ informa
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OECD SIDS m- / p-CRESOL MIXTURE I U
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