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m-Cresol - ipcs inchem

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OECD SIDS<br />

p-CRESOL<br />

4. ECOTOXICITY ID: 106-44-5<br />

DATE: 24.05.2004<br />

- Test temperature: 14 degrees C<br />

- Dissolved oxygen: 6.5 mg/l (84.5% of saturation)<br />

- pH: 8.1<br />

- Photoperiod: 16 h light, 8 h dark<br />

Reliability : (1) valid without restriction<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

detailed documentation of test procedure and test conditions<br />

Flag : Critical study for SIDS endpoint<br />

22.10.2001 (79)<br />

Type : flow through<br />

Species : Pimephales promelas (Fish, fresh water)<br />

Exposure period : 96 hour(s)<br />

Unit : mg/l<br />

LC50 : = 28.6<br />

Limit test :<br />

Analytical monitoring : yes<br />

Method : EPA OPP 72-1<br />

Year : 1974<br />

GLP : no data<br />

Test substance : other TS: p-cresol, purity not noted<br />

Remark : Lethargic and loss of equilibrium at 22.7 mg/l<br />

Test condition : DILUTION WATER<br />

- Source: well water<br />

- Hardness: 707.3 mg CaCO3/l<br />

- Conductance: 1212.3 µmhos/cm at 25 degrees C<br />

TEST SYSTEM<br />

- Concentrations: 1:2 dilution series<br />

- Number of replicates: 2<br />

- fish per replicate: 10<br />

- Test temperature: 14 degrees C<br />

- Dissolved oxygen: 6.5 mg/l (84.5% of saturation)<br />

- pH: 8.1<br />

- Photoperiod: 16 h light, 8 h dark<br />

Reliability : (1) valid without restriction<br />

Test procedure comparable to standard method and in<br />

accordance with generally accepted scientific standards;<br />

detailed documentation of test procedure and test conditions<br />

Flag : Critical study for SIDS endpoint<br />

22.10.2001 (79)<br />

Type : static<br />

Species : Salmo trutta (Fish, fresh water, marine)<br />

Exposure period : 96 hour(s)<br />

Unit : mg/l<br />

LC50 : = 4.4<br />

Limit test :<br />

Analytical monitoring : no<br />

Method :<br />

Year : 1969<br />

GLP : no<br />

Test substance : other TS: p-cresol, purity of "practical grade"<br />

Method : 10 acclimated fish exposed per concentration, 20 served as<br />

control<br />

Result : LC50 (6 h) = 4.7 mg/l<br />

LC50 (24 h) = 4.4 mg/l<br />

LC50 (48 h) = 4.4 mg/l<br />

Test condition : 12 degrees C; reconstituted water<br />

UNEP PUBLICATIONS 223

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