m-Cresol - ipcs inchem

OECD SIDS
m-CRESOL
4. ECOTOXICITY ID: 108-39-4
DATE: 24.05.2004
Species : other bacteria: gentechnologically constructed luminescent bacteria
originating from wastewater treatment plant
Exposure period : 30 minute(s)
Unit : mg/l
EC50 : 68 measured/nominal
Analytical monitoring : no
Method : other: Microtox assay
Year : 1986
GLP : no data
Test substance : other TS: m-cresol, no purity reported
Remark : Inhibition of bioluminescence
Modified microorganisms used which represent the metabolic potentials
present in a wastewater treatment plant and some properties of a marine
organism, but which are not identical to any known species in natural
environments
Test condition : - Wastewater bacteria (Eschericia coli) which were obtained from a
wastewater treatment plant
- Bacteria obtained the luciferase operon of Vibrio fischeri by transfer from
luminescent E. coli
- Incubation at 20 °C
- Result calculated from the difference of the luminescence between
controls and test substance taking into account the light emissions at 0 and
20 °C
Reliability : (3) invalid
Unsuitable test system. Organisms are of marine origin. Method is not
appropriate for the hazard assessment of chemicals.
07.05.2004 (95)
Type : aquatic
Species : Escherichia coli (Bacteria)
Exposure period : 2 hour(s)
Unit : mg/l
EC50 : 1000
Method :
Year : 1954
GLP : no
Test substance : other TS: m-cresol, no purity reported
Result : endpoint related to growth inhibition
no effect on cell size
Test condition : 37 degrees C
Reliability : (3) invalid
Methodological deficiencies
12.05.2004 (96)
Type : aquatic
Species : Escherichia coli (Bacteria)
Exposure period :
Unit : mg/l
TT : 600
Analytical monitoring : no
Method :
Year : 1959
GLP : no
Test substance : other TS: m-cresol, no purity reported
Method : test organisms isolated from river water
endpoint: inhibition of glucose metabolism
Remark : TT = toxicity treshold; determined at 5 % effect compared to
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